Basal ganglia--hippocampal interactions support the role of the hippocampal formation in sensorimotor integration

Experimental Neurology
Nicholas E Hallworth, B H Bland

Abstract

Experiments were carried out to evaluate whether neural activity in the basal ganglia is functionally related to the neural activity underlying mechanisms of theta band oscillation and synchrony in the hippocampal formation. Experiment 1 demonstrated that electrical stimulation administered to the substantia nigra, globus pallidus (GP) and caudate-putamen (CPu) in urethane anesthetized rats elicited theta field activity in the hippocampal formation. Subsequent microinfusion of the local anesthetic procaine hydrochloride into the medial septum reversibly abolished this effect. In Experiment 2, single cell discharge profiles established for 152 cells recorded in nuclei of the basal ganglia resulted in 101 (66%) being classified as theta-related and 51 (34%) classified as nonrelated. Theta-related cells were further subclassified as tonic theta-ON cells (n = 79) and tonic theta-OFF (n = 22). Tonic theta-ON and tonic theta-OFF cells displayed irregular or regular (tonic) discharge patterns. Rhythmic discharge patterns did not occur in any theta-related cells in the nuclei of the basal ganglia. However, analyses using Kaneoke and Vitek's [J. Neurosci. Methods 68, (1996) 211] algorithms revealed that 51/101 (50%) theta-related cells ...Continue Reading

References

May 1, 1989·The Journal of Comparative Neurology·B M Spann, I Grofova
Oct 1, 1989·Trends in Neurosciences·R L AlbinJ B Penney
Apr 10, 1989·Neuroscience Letters·M SabatinoV La Grutta
Jan 1, 1986·Progress in Neurobiology·B H Bland
Oct 24, 1985·Neuroscience Letters·M SabatinoV La Grutta
Jan 1, 1996·Critical Reviews in Neurobiology·S P WiseC R Gerfen
Feb 1, 1991·Molecular and Cellular Neurosciences·S L DrinnanS R Vincent

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Citations

May 11, 2005·Brain Research. Developmental Brain Research·Kathleen M GuthrieRichard T Robertson
Jul 30, 2010·Journal of Cognitive Neuroscience·Talya SadehAnat Maril
Mar 13, 2014·Neuron·Tale L BjerknesMay-Britt Moser
Aug 31, 2012·Epilepsy Research and Treatment·J A Kiernan
Sep 23, 2008·Epilepsy & Behavior : E&B·Norbert KovacsJozsef Janszky
Nov 26, 2015·Neuroscience·J R López RuizS H Duenas Jimenez
Nov 13, 2007·Neurobiology of Aging·Susanne RutzJean-Christophe Cassel
Oct 4, 2011·Progress in Neurobiology·Marsha R Penner, Sheri J Y Mizumori
Feb 11, 2012·Neuroscience Letters·Ulrich SeidlPhilipp A Thomann
Jul 20, 2016·Journal of Neural Engineering·R MarecekM Brazdil
May 5, 2021·Hippocampus·Carlos Del Rio-Bermudez, Mark S Blumberg

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