Basal Hormones and Biochemical Markers as Predictors of Overtraining Syndrome in Male Athletes: The EROS-BASAL Study

Journal of Athletic Training
Flavio A Cadegiani, Claudio E Kater

Abstract

Overtraining syndrome (OTS) and related conditions cause decreased training performance and fatigue through an imbalance among training volume, nutrition, and recovery time. No definitive biochemical markers of OTS currently exist. To compare muscular, hormonal, and inflammatory parameters among OTS-affected athletes, healthy athletes, and sedentary controls. Cross-sectional study. Laboratory. Fifty-one men aged 18 to 50 years (14 OTS-affected athletes [OTS group], 25 healthy athletes [ATL group], and 12 healthy sedentary participants [NCS group]), with a body mass index of 20 to 30.0 kg/m2 (sedentary) or 20 to 33.0 kg/m2 (athletes), recruited through social media. All 39 athletes performed both endurance and resistance sports. We measured total testosterone, estradiol, insulin-like growth factor 1, thyroid-stimulating hormone, free thyronine, total and fractioned catecholamines and metanephrines, lactate, ferritin, creatinine, creatine kinase, erythrocyte sedimentation rate, C-reactive protein, lipid profile, hemogram, and testosterone : estradiol, testosterone : cortisol, neutrophil : lymphocyte, platelet: lymphocyte, and catecholamine : metanephrine ratios. Each parameter was statistically analyzed through 3-group comparison...Continue Reading

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Citations

Sep 25, 2019·BMC Sports Science, Medicine and Rehabilitation·Flavio A Cadegiani, Claudio E Kater
Jul 18, 2020·International Journal of Sports Physiology and Performance·Clementine GrandouFranco M Impellizzeri
Feb 23, 2020·Frontiers in Endocrinology·Anthony C Hackney
Jan 7, 2021·International Journal of Sports Physiology and Performance·Flavio A CadegianiClaudio E Kater
Feb 23, 2021·Der Orthopäde·Maximilian M DelsmannTim Rolvien
Feb 28, 2021·BMJ Case Reports·Flavio CadegianiCarlos G Wambier
Mar 5, 2021·International Journal of Sports Physiology and Performance·Travis AndersonClaudio E Kater
Sep 10, 2021·Sports Health·Justin CarrardArno Schmidt-Trucksäss

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