PMID: 8594081Oct 1, 1995Paper

Basaloid folliculolymphoid hyperplasia with alopecia as an expression of mycosis fungoides (CTCL)

Journal of Cutaneous Pathology
S KossardM Killingsworth

Abstract

Follicular mucinosis, papules, cysts and comedones have been previously described as expressions of follicular involvement by mycosis fungoides. We report a patient with mycosis fungoides who developed extensive alopecia. Multiple scalp biopsies showed perifollicular and intrafollicular infiltrate of lymphocytes but no evident follicular mucinosis. On transverse sections many of the follicles showed an absence of differentiation towards hair sheath, canal, sebaceous gland or hair formation, but instead formed undifferentiated basaloid structures. These basaloid structures showed transition from atrophic telogen follicles to hypertrophic basaloid islands infiltrated by lymphocytes, resembling the pattern previously described in cutaneous lymphadenoma. Immunophenotyping showed a predominance of helper T-cells which, on ultrastructural examination, showed cerebriform nuclei. The unusual histological findings in our case may be analogous to the hyperplasia seen in sweat glands in syringotropic mycosis fungoides (syringolymphoid hyperplasia), and we propose the term basaloid folliculolymphoid hyperplasia to describe this feature. Basaloid follicular hyperplasia has been previously described as a component of follicular mucinosis but...Continue Reading

References

Apr 1, 1992·Journal of Cutaneous Pathology·J WechslerE S Zafrani
Jan 1, 1992·Dermatology : International Journal for Clinical and Investigative Dermatology·G Burg, C Schmöckel
Jul 1, 1992·The British Journal of Dermatology·S Oliwiecki, J Ashworth
Apr 1, 1991·Mayo Clinic Proceedings·D A MehreganS A Muller
Feb 1, 1991·The American Journal of Surgical Pathology·D J Santa CruzJ T Headington
Mar 1, 1989·Journal of the American Academy of Dermatology·L E GibsonM S Peters
Jan 1, 1984·The British Journal of Dermatology·F Vakilzadeh, E B Bröcker
Dec 1, 1994·Journal of Cutaneous Pathology·M M TomaszewskiW D James
Jun 1, 1994·The British Journal of Dermatology·B ZelgerB Zelger
Sep 1, 1993·Pediatric Dermatology·M de la Luz Orozco-CovarrubiasR Ruiz-Maldonado
Mar 1, 1993·The British Journal of Dermatology·R Botella, R M Mackie

❮ Previous
Next ❯

Citations

May 19, 2005·The American Journal of Dermatopathology·Steven Kossard, Paul Weller
Aug 28, 2007·The American Journal of Surgical Pathology·Pedram Gerami, Joan Guitart
Dec 5, 1998·The Australasian Journal of Dermatology·J R Sullivan, S Kossard
Sep 21, 2010·Annals of Diagnostic Pathology·Jeong Hee Cho-VegaFrancisco Vega
Mar 20, 2013·Journal of Cutaneous Pathology·Margareth Pierre-LouisMaria K Hordinsky
Sep 7, 2000·Ceskoslovenská patologie·F FakanS Námĕstek
Nov 7, 2006·Journal of Cutaneous Pathology·J Andrew CarlsonJoseph Schwartz
Dec 6, 2007·Journal of Cutaneous Pathology·Pedram Gerami, Joan Guitart
Jul 20, 1999·Dermatologic Clinics·C Jaworsky, A C Gilliam
Dec 12, 2001·Journal of Cutaneous Pathology·M J FlaigC A Sander
Feb 18, 2003·The British Journal of Dermatology·A GarcovichG Massi
Oct 29, 2021·Dermatology and Therapy·Eve LebasArjen F Nikkels
Jun 17, 2021·The American Journal of Dermatopathology·Steven KossardDedee Murrell

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenoma, Islet Cell

Islet Cell Adenoma arises in the islet cells, which are insulin producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Adenoma here.