Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial

Journal of the American Society of Hypertension : JASH
Carolyn H StillSPRINT Study Research Group

Abstract

The Systolic Blood Pressure Intervention Trial (SPRINT) will compare treatment to a systolic blood pressure goal of <120 mm Hg to treatment to the currently recommended goal of <140 mm Hg for effects on incident cardiovascular, renal, and neurologic outcomes including cognitive decline. The objectives of this analysis are to compare baseline characteristics of African American (AA) and non-AA SPRINT participants and explore factors associated with uncontrolled blood pressure (BP) by race. SPRINT enrolled 9361 hypertensive participants aged older than 50 years. This cross-sectional analysis examines sociodemographics, baseline characteristics, and study measures among AAs compared with non-AAs. AAs made up 31% of participants. AAs (compared with non-AAs) were younger and less frequently male, had less education, and were more likely uninsured or covered by Medicaid. In addition, AAs scored lower on the cognitive screening test when compared with non-AAs. Multivariate logistic regression analysis found BP control rates to <140/90 mm Hg were higher for AAs who were male, had higher number of chronic diseases, were on diuretic treatment, and had better medication adherence. SPRINT is well poised to examine the effects of systolic b...Continue Reading

References

Apr 7, 2005·JAMA : the Journal of the American Medical Association·Jackson T WrightUNKNOWN ALLHAT Collaborative Research Group
Sep 1, 2005·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Finlay A McAlisterUNKNOWN Canadian Hypertension Education Program
Mar 3, 2007·Clinical Chemistry·Andrew S LeveyUNKNOWN Chronic Kidney Disease Epidemiology Collaboration
Jul 7, 2007·Blood Pressure·Kenneth JamersonUNKNOWN ACCOMPLISH Investigators
Apr 2, 2008·The New England Journal of Medicine·Nigel S BeckettUNKNOWN HYVET Study Group
Dec 5, 2008·The New England Journal of Medicine·Kenneth JamersonUNKNOWN ACCOMPLISH Trial Investigators
May 13, 2009·Archives of Internal Medicine·Jackson T WrightUNKNOWN ALLHAT Collaborative Research Group
Oct 6, 2010·Hypertension·John M FlackUNKNOWN International Society on Hypertension in Blacks
Dec 20, 2013·Circulation·Alan S GoUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Jan 22, 2014·Circulation·Alan S GoUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Jun 7, 2014·Clinical Trials : Journal of the Society for Clinical Trials·Walter T AmbrosiusUNKNOWN SPRINT Study Research Group
Oct 5, 2015·Journal of Acupuncture and Meridian Studies·Jan Still

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Citations

Nov 1, 2015·International Journal of Cardiology·Huibo WangWeiling Huang
Oct 4, 2016·Progress in Cardiovascular Diseases·Stephen K WilliamsGbenga Ogedegbe
Oct 7, 2017·American Journal of Hypertension·Carolyn H StillUNKNOWN SPRINT Writing Group
May 4, 2016·Current Opinion in Cardiology·Amanda BennettSelim R Krim
Nov 20, 2016·The Journal of Clinical Hypertension·Carlos J RodriguezUNKNOWN SPRINT Research Group

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