PMID: 9541214Apr 16, 1998Paper

Basement membrane-like structures occurring on the surface of dental papilla mesenchymal cells during odontogenesis in the monkey Macaca fuscata

European Journal of Oral Sciences
T Sawada, S Inoue

Abstract

The aim of this study was to examine the nature of a basement membrane-like structure occurring along the surface of dental papilla cells during odontogenesis. The tooth germs of Japanese macaques (Macaca fuscata) were prepared for both ultrastructural and immunohistochemical studies. Characteristic discrete structures which resembled basement membranes were observed along the surface of the dental papilla cells, preodontoblasts, and also of the odontoblasts. Immunoperoxidase staining showed that these structures contained major basement membrane components including laminin, heparan sulfate proteoglycan, type IV collagen, as well as fibronectin. They tended to be less prominent along dental pulp fibroblasts and fully developed odontoblasts in comparison with those along the papilla cells localized close to the basement membrane of the inner enamel epithelium. Therefore, possible roles of these basement membrane-like structures would be: 1) to support the cells, 2) to momentarily secure the appropriate positions of differentiating mesenchymal cells, and 3) to regulate epithelial-mesenchymal interactions for odontoblast differentiation.

Citations

Dec 7, 2007·Archives of Oral Biology·Sausan Al Kawas, Hershey Warshawsky
Oct 6, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·K FriedC Hildebrand
Jun 2, 2005·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Hiroko Ida-YonemochiTakashi Saku
Jun 15, 2007·The Journal of Biological Chemistry·Ming XieHidetaka Sakai

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basement Membranes

Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. Here is the latest research on basement membranes.