Basement Membranes in Development and Disease

Current Topics in Developmental Biology
Rei Sekiguchi, Kenneth M Yamada

Abstract

The basement membrane is a thin but dense, sheet-like specialized type of extracellular matrix that has remarkably diverse functions tailored to individual tissues and organs. Tightly controlled spatial and temporal changes in its composition and structure contribute to the diversity of basement membrane functions. These different basement membranes undergo dynamic transformations throughout animal life, most notably during development. Numerous developmental mechanisms are regulated or mediated by basement membranes, often by a combination of molecular and mechanical processes. A particularly important process involves cell transmigration through a basement membrane because of its link to cell invasion in disease. While developmental and disease processes share some similarities, what clearly distinguishes the two is dysregulation of cells and extracellular matrices in disease. With its relevance to many developmental and disease processes, the basement membrane is a vitally important area of research that may provide novel insights into biological mechanisms and development of innovative therapeutic approaches. Here we present a review of developmental and disease dynamics of basement membranes in Caenorhabditis elegans, Dros...Continue Reading

Citations

Nov 20, 2018·Journal of Cellular and Molecular Medicine·Laura Cristina CeafalanMihaela Gherghiceanu
Apr 9, 2019·Current Protocols in Cell Biology·Rei Sekiguchi, Belinda Hauser
Jun 11, 2019·International Journal of Experimental Pathology·Kenneth M YamadaShaohe Wang
Jun 4, 2020·Marine Drugs·Adrian Florian BălașaAlexandru Mihai Grumezescu
Jan 30, 2020·British Journal of Cancer·Elisa D'ArcangeloAlison P McGuigan
Aug 28, 2020·Frontiers in Cell and Developmental Biology·Min LiuRong Zhou
Feb 10, 2019·International Journal of Molecular Sciences·Miguel QuintanillaEster Martín-Villar
Sep 27, 2019·International Journal of Molecular Sciences·Ha Thi Thu NguyenToshitaka Oohashi
Dec 4, 2020·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Raphaël BoncheSandrine Pizette
Nov 1, 2018·The Journal of Biological Chemistry·Carl DarrisBilly G Hudson
Jan 19, 2021·Critical Reviews in Microbiology·Bryn ShortS Lorraine Martin
Feb 7, 2021·Nature Reviews. Nephrology·Elena Torban, Sergei Y Sokol
Jan 22, 2021·ACS Biomaterials Science & Engineering·Sofia SantiAntonella Motta
Nov 17, 2020·Tissue Barriers·Mehmet Kaya, Bulent Ahishali
Feb 3, 2021·Development·Véronique Van De BorStéphane Noselli
Jun 26, 2020·Developmental Cell·Yutaka MatsubayashiBrian Marc Stramer
Apr 16, 2021·Metabolism: Clinical and Experimental·Anna GoddiRonald N Cohen
Apr 23, 2020·Journal of Cell Science·José C Pastor-Pareja
Sep 18, 2020·Journal of Cell Science·Claire LeclechAbdul I Barakat
May 30, 2020·Development·David A Cruz Walma, Kenneth M Yamada
Jun 26, 2021·ACS Biomaterials Science & Engineering·Christos Panagiotis TasiopoulosMy Hedhammar
Aug 13, 2021·Bioscience Reports·Erin BolandTom Van Agtmael
Nov 5, 2020·Experimental Eye Research·Willi HalfterPaul Bernhard Henrich
Sep 3, 2021·Nihon yakurigaku zasshi. Folia pharmacologica Japonica·Akira SugiyamaHideyuki Yamawaki
Dec 16, 2021·Physical Biology·Andrew D DoyleKenneth M Yamada

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