Basic autonomy as a fundamental step in the synthesis of life

Artificial Life
Kepa Ruiz-Mirazo, A Moreno

Abstract

In the search for the primary roots of autonomy (a pivotal concept in Varela's comprehensive understanding of living beings), the theory of autopoiesis provided an explicit criterion to define minimal life in universal terms, and was taken as a guideline in the research program for the artificial synthesis of biological systems. Acknowledging the invaluable contribution of the autopoietic school to present biological thinking, we offer an alternative way of conceiving the most basic forms of autonomy. We give a bottom-up account of the origins of "self-production" (or self-construction, as we propose to call it), pointing out which are the minimal material and energetic requirements for the constitution of basic autonomous systems. This account is, indeed, committed to the project of developing a general theory of biology, but well grounded in the universal laws of physics and chemistry. We consider that the autopoietic theory was formulated in highly abstract terms and, in order to advance in the implementation of minimal autonomous systems (and, at the same time, make major progress in exploring the origins of life), a more specific characterization of minimal autonomous systems is required. Such a characterization will not b...Continue Reading

References

Sep 1, 1992·European Journal of Biochemistry·V P Skulachev
Mar 1, 1992·Acta Biotheoretica·A Moreno Bergareche, J Fernández Ostolaza
Jan 1, 1988·Bio Systems·G R Fleischaker
Jan 1, 1988·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·H J MorowitzD W Deamer
Mar 7, 1986·Journal of Theoretical Biology·S A Kauffman
May 1, 1974·Currents in Modern Biology·F G VarelaR Uribe
Sep 1, 1971·The Bulletin of Mathematical Biophysics·R Rosen
May 1, 1994·The American Journal of Hospice & Palliative Care·M A Smith
Aug 8, 1996·Nature·D H LeeM R Ghadiri
Mar 24, 1998·Acta Anaesthesiologica Scandinavica·U KleinR Gottschall
Aug 1, 1998·Acta Ophthalmologica Scandinavica·C NduagubaJ Caprioli
Apr 13, 2000·Proceedings of the National Academy of Sciences of the United States of America·D SegréD Lancet
Feb 24, 2001·Nature·J W SzostakP L Luisi
Mar 16, 2001·Trends in Biotechnology·J K Lanyi, A Pohorille
Feb 14, 2002·Trends in Biotechnology·Andrew Pohorille, David Deamer
Oct 17, 2002·The Anatomical Record·Pier Luigi Luisi
Oct 17, 2002·The Anatomical Record·Catherine E Morris
Feb 21, 2003·Astrobiology·David DeamerLouis J Allamandola

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Citations

Sep 30, 2009·Journal of Molecular Evolution·Aron IngerDoron Lancet
Jul 25, 2007·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Kepa Ruiz-Mirazo, Fabio Mavelli
Oct 17, 2012·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Leonardo Bich, Luisa Damiano
Jan 20, 2007·Bulletin of Mathematical Biology·Felix OlasagastiFederico Morán
May 19, 2007·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Fabio Mavelli, Kepa Ruiz-Mirazo
Feb 23, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J Scott Jordan
Feb 5, 2013·Artificial Life·Xabier E Barandiaran, Matthew D Egbert
Oct 28, 2008·The International Journal of Biochemistry & Cell Biology·Ricard V Solé
Sep 15, 2007·Bio Systems·Xabier Barandiaran, Kepa Ruiz-Mirazo
Aug 22, 2007·Bio Systems·Anthony Chemero, Michael T Turvey
Aug 29, 2007·Bio Systems·Chrisantha Fernando, Jonathan Rowe
Aug 6, 2009·EMBO Reports·Arantza Etxeberria, Kepa Ruiz-Mirazo
Jul 1, 2009·Topics in Cognitive Science·William Bechtel
Dec 5, 2012·Angewandte Chemie·Stephen Mann
Oct 23, 2016·Bio Systems·Leonardo Bich, Alvaro Moreno
May 20, 2015·Journal of Theoretical Biology·Andrés de la EscosuraKepa Ruiz-Mirazo
Mar 11, 2015·Journal of Theoretical Biology·Maël Montévil, Matteo Mossio
May 23, 2012·Progress in Biophysics and Molecular Biology·Charles T Wolfe
Aug 26, 2014·Frontiers in Human Neuroscience·Matthew D Egbert, Xabier E Barandiaran
Aug 16, 2016·Progress in Biophysics and Molecular Biology·Matteo MossioGiuseppe Longo
Aug 18, 2016·Progress in Biophysics and Molecular Biology·Maël MontévilGiuseppe Longo
Oct 12, 2016·History and Philosophy of the Life Sciences·Alvaro Moreno
Nov 18, 2018·Interface Focus·Artemy Kolchinsky, David H Wolpert
Feb 26, 2010·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Kepa Ruiz-MirazoAlvaro Moreno
Jun 5, 2019·Journal of Bioethical Inquiry·Denis Larrivee, Michele Farisco
Sep 15, 2019·Acta Biotheoretica·Samuel Cusimano, Beckett Sterner
Aug 7, 2017·Beilstein Journal of Organic Chemistry·Ben Shirt-EdissKepa Ruiz-Mirazo
Dec 19, 2019·Frontiers in Psychology·Isaac Hernández, Davide Vecchi
Jul 6, 2019·Frontiers in Physiology·Stuart A Newman
Sep 26, 2020·Frontiers in Psychology·Juan M LoaizaSune V Steffensen
Sep 1, 2018·History and Philosophy of the Life Sciences·Francesca MicheliniDirk Stederoth
Mar 7, 2020·Frontiers in Physiology·Leonardo BichAna M Soto
Nov 6, 2015·Frontiers in Neurology·Andrea Schiavio, Eckart Altenmüller
Aug 25, 2021·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Nino LauberKepa Ruiz-Mirazo

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