Basic characteristics and representativeness of the German Disease Analyzer database


International Journal of Clinical Pharmacology and Therapeutics
Wolfgang RathmannKarel Kostev

Abstract

The aim of this study was to evaluate the representativeness of diagnoses in the Disease Analyzer (DA) database for major chronic diseases (cancer, dementia, diabetes). DA contains anonymized longitudinal data on drug prescriptions, diagnoses as well as medical and demographic data directly obtained from the computer system of a representative sample of practices throughout Germany. DA contains data from 2,498 practices with 7.8 million patients (2017). The distribution and sex-specific incidence of various cancer subsites among new cancer cases, the age- and sex-specific prevalence of dementia, and the prevalence of diabetes were assessed. National reference data were obtained from official sources. Mean age (43 years) and sex distribution (47% men) of primary care patients in DA were similar to the German population. Among incident cancer cases, there was good agreement between DA data and national data with respect to the various cancer subsites (e.g., breast cancer: DA 17%; reference: 15%). Furthermore, sex distribution was largely similar. The age distribution of prevalent dementia was similar to national reference data, both in men (80 - 84 years: DA: 26.8%; reference: 27.0%) and in women (80 - 84 years: DA: 24.6%; refere...Continue Reading

Citations

Mar 14, 2019·Journal of Diabetes Science and Technology·Karel KostevStefan Pscherer
Mar 29, 2019·Rheumatology International·Karel Kostev
Dec 8, 2019·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L JacobK Kostev
Mar 21, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Karel Kostev
Dec 5, 2019·Digestive Diseases and Sciences·Christian LabenzJörn M Schattenberg
Jun 25, 2020·Ear, Nose, & Throat Journal·David Ulrich SeidelJonas Jae-Hyun Park
Jun 9, 2020·Diabetic Medicine : a Journal of the British Diabetic Association·L van den BoomK Kostev
Jul 31, 2020·Alimentary Pharmacology & Therapeutics·Christian LabenzKarel Kostev
May 8, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·I KyvernitakisP Hadji
Aug 18, 2020·European Journal of Clinical Pharmacology·Thomas Grimmsmann, Wolfgang Himmel
Sep 3, 2020·Fortschritte der Neurologie-Psychiatrie·Jens BohlkenKarel Kostev
Sep 12, 2019·Journal of Cancer Research and Clinical Oncology·Christian TanislavKarel Kostev
Sep 20, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Julius L KatzmannUlrich Laufs
Nov 27, 2018·Rheumatology International·Louis JacobKarel Kostev
Mar 19, 2019·Journal of Alzheimer's Disease : JAD·Jens Bohlken, Karel Kostev
Jul 1, 2019·Journal of Vestibular Research : Equilibrium & Orientation·David Ulrich SeidelKarel Kostev
Nov 24, 2019·International Journal of Colorectal Disease·Leif SchiffmannMatthias Kalder
Feb 25, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·U StumpfK Kostev
Jun 11, 2020·Journal of Cancer Research and Clinical Oncology·Leif SchiffmannMatthias Kalder
Sep 15, 2020·Hepatology Communications·Christian LabenzJörn M Schattenberg
May 20, 2020·Breast Cancer Research and Treatment·Laura BachMatthias Kalder
Aug 28, 2020·Current Medical Research and Opinion·Nanette C SchlootCarolina Piras de Oliveira
Feb 11, 2019·Journal of Cancer Research and Clinical Oncology·Louis Jacob, Karel Kostev
Mar 20, 2020·Journal of Cancer Research and Clinical Oncology·Louis JacobMatthias Kalder
Jul 11, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C Tanislav, K Kostev
Feb 5, 2019·Journal of Alzheimer's Disease : JAD·Louis JacobKarel Kostev
Oct 11, 2020·Digestive Diseases and Sciences·Christian LabenzJörn M Schattenberg
Oct 24, 2020·Journal of Diabetes Science and Technology·Louisa van den BoomKarel Kostev

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