Apr 7, 1975

Basic phospholipase of Naja nigricollis venom

Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles
C DumareyP Boquet


It is confirmed that N. nigricollis venom contains several phospholipases one of these is a basic phospholipase A. This enzyme is toxic for mice when injected intravenously. In vitro it reacts on egg yolk lecithin producing lysolecithin and prevents the phenomenon of blood clotting. An immunological identity has been established between this basic phospholipase and two acidic phospholipases present in the same venom.

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Mentioned in this Paper

Snake Venoms
Lecithinum, lecithin, Homeopathic preparation
Phospholipase A Activity
Naja nigricollis
Blood Clot
Lethal Dose 50

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