PMID: 9163767Jun 1, 1997Paper

Basic research in endometriosis

Obstetrics and Gynecology Clinics of North America
K L Sharpe-Timms

Abstract

A more thorough understanding of the mechanisms associated with the cause and pathophysiology of endometriosis may help in the development of new diagnostic and therapeutic methods for the management of endometriosis. Research has begun to enhance our understanding of endometriosis by demonstrating the differences and similarites between eutopic and ectopic endometrium, and by characterizing the peritoneal environment. Animal models have been developed and validated to conduct studies that are ethically impossible in women. Recently, cell culture models, using purified populations of cells from endometriotic lesions, have provided an appropriate in vitro endometriosis model to study the language by which cells communicate; to evaluate the biochemical effects of steroids, growth factors, pharmacological agents and immunomodulatory agents on the cells; and to study the effects of endometriosis on reproduction.

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Citations

Mar 24, 2004·Fertility and Sterility·Zeev Blumenfeld
Oct 10, 2002·Fertility and Sterility·Mario VignaliPaola Viganò
Oct 10, 2002·Fertility and Sterility·Kathy L Sharpe-TimmsGary M Horowitz
Jun 28, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·D VinatierP Dufour
Apr 13, 2002·Annals of the New York Academy of Sciences·Kathy L Sharpe-Timms, Kathryn E Cox
Mar 1, 2006·Women's Health·Luigi FedeleAlessandro Bulfoni
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Feb 3, 2012·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Qiao-Ying Jiang, Rui-Jin Wu
Oct 26, 2011·Journal of Minimally Invasive Gynecology·Juliana Menezes SiqueiraRogério Saad-Hossne
Jun 14, 2008·Reproductive Biomedicine Online·R GajbhiyeV Khole
Nov 27, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Paolo VercelliniPier Giorgio Crosignani
May 26, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·Paola ViganòPaolo Vercellini
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Oct 12, 2001·Annals of the New York Academy of Sciences·K L Sharpe-Timms
May 2, 2009·Drugs·Paolo VercelliniPier Giorgio Crosignani

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