Basic Science and Clinical Application of Reamed Sources for Autogenous Bone Graft Harvest

The Journal of the American Academy of Orthopaedic Surgeons
Thomas F Higgins, Lucas S Marchand

Abstract

Autologous bone graft remains the only clinically available source of graft material with osteogenic, osteoinductive, and osteoconductive properties. Although iliac crest autologous bone graft has long served as the benchmark, reamed autogenous bone graft offers several advantages. Reamed autograft has a biochemical and cellular profile that is at least equivalent, and perhaps superior, to that of iliac crest autograft. In addition, larger volumes of reamed autograft can be obtained via less-invasive techniques, giving surgeons an accessible source of mesenchymal stem cells that can be reliably and repeatedly harvested. Early clinical experience involving reamed autogenous bone graft in the management of nonunion, bone defects, and arthrodesis has been encouraging and has demonstrated the necessary properties to warrant regular consideration of reamed graft for these applications.

References

Mar 7, 2001·The Journal of Trauma·J P FrölkeH J Haarman
Feb 13, 2004·The Journal of Trauma·Florian HoegelNorbert P Suedkamp
Oct 12, 2004·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Jan Paul M FrölkeHenk J Th M Haarman
Jan 25, 2005·Bone·Sabine WenischReinhard Schnettler
Sep 29, 2005·Injury·Peter V GiannoudisEleftherios Tsiridis
Apr 25, 2006·Orthopedics·Stephen C Brawley, R Bruce Simpson
Mar 3, 2007·The Journal of Bone and Joint Surgery. American Volume·William G De LongTracy Watson
Nov 14, 2007·The Journal of Bone and Joint Surgery. British Volume·T O HammerC A Müller
Jul 26, 2008·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ryan M PorterChristopher H Evans
Oct 9, 2008·Clinical Orthopaedics and Related Research·Mohan V BelthurJohn E Herzenberg
Jun 23, 2009·The Spine Journal : Official Journal of the North American Spine Society·David H KimScott G Tromanhauser
Nov 26, 2009·The Orthopedic Clinics of North America·David J Hak, Jason L Pittman
Nov 26, 2009·The Orthopedic Clinics of North America·Todd A McCallTimothy G Weber
Nov 26, 2009·The Orthopedic Clinics of North America·Janet D Conway
Dec 26, 2009·Journal of Orthopaedic Trauma·Andres J QuinteroHans-Christoph Pape
Jan 19, 2011·International Orthopaedics·George CoxPeter V Giannoudis
Apr 6, 2011·The Journal of Bone and Joint Surgery. British Volume·G CoxP V Giannoudis
Oct 5, 2011·Injury·Nikolaos K KanakarisPeter V Giannoudis
Aug 11, 2012·The Journal of Bone and Joint Surgery. American Volume·Bryan J LoefflerMichael J Bosse
Jan 15, 2013·Cytotherapy·Valeria RasiniRichard Schäfer
Jul 23, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Dimitrios KouroupisPeter V Giannoudis
Nov 20, 2015·Journal of Orthopaedic Trauma·Aaron NauthPeter Giannoudis
Jan 10, 2016·Injury·Pamela KuehlfluckUNKNOWN HTRG-Heidelberg Trauma Research Group
Mar 5, 2016·International Journal of Molecular Medicine·Dirk HenrichCaroline Seebach

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

© 2022 Meta ULC. All rights reserved