Bat-borne virus diversity, spillover and emergence.

Nature Reviews. Microbiology
Michael LetkoVincent Munster

Abstract

Most viral pathogens in humans have animal origins and arose through cross-species transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus, Nipah virus, Hendra virus, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory coronavirus (MERS-CoV) and SARS-CoV-2, have been linked back to various bat species. Despite decades of research into bats and the pathogens they carry, the fields of bat virus ecology and molecular biology are still nascent, with many questions largely unexplored, thus hindering our ability to anticipate and prepare for the next viral outbreak. In this Review, we discuss the latest advancements and understanding of bat-borne viruses, reflecting on current knowledge gaps and outlining the potential routes for future research as well as for outbreak response and prevention efforts.

References

Jun 19, 1995·The Medical Journal of Australia·L A SelveyJ W Sheridan
Nov 13, 2001·Journal of Neurovirology·J E Reid, A C Jackson
Mar 7, 2002·Microbes and Infection·Kaw Bing ChuaSai Kit Lam
Mar 26, 2005·The EMBO Journal·Wenhui LiMichael Farzan
Jul 7, 2005·Proceedings of the National Academy of Sciences of the United States of America·Matthew I BonaparteChristopher C Broder
Jul 19, 2005·Emerging Infectious Diseases·Jean-Marc ReynesJean-Louis Sarthou
Oct 1, 2005·Science·Wendong LiLin-Fa Wang
Dec 2, 2005·Nature·Eric M LeroyRobert Swanepoel
Jul 19, 2006·Clinical Microbiology Reviews·Charles H CalisherTony Schountz
Mar 1, 2007·Emerging Infectious Diseases·Stephen P LubyThomas G Ksiazek
May 15, 2007·Journal of Comparative Pathology·D J MiddletonP W Daniels
Jun 27, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kaw Bing ChuaLin-Fa Wang
Apr 26, 2008·Veterinary Immunology and Immunopathology·Tsutomu OmatsuYasuhiro Yoshikawa
Aug 12, 2008·Journal of Wildlife Diseases·Felix R JacksonCharles E Rupprecht
Sep 2, 2008·Virus Research·M F AlmeidaE Massad
Oct 22, 2008·Lancet·Longde WangMary Elizabeth Wilson
Nov 28, 2008·Journal of Virology·Nolwenn JouvenetPaul D Bieniasz
Nov 28, 2008·Proceedings of the National Academy of Sciences of the United States of America·Michelle M BeckerMark R Denison
Dec 19, 2008·Journal of Virology·Toshie SakumaJiro Yasuda
Jan 31, 2009·Proceedings of the National Academy of Sciences of the United States of America·Rachel L KaletskyPaul Bates
Aug 4, 2009·PLoS Pathogens·Jonathan S TownerPierre E Rollin
Sep 16, 2009·Emerging Infectious Diseases·Stephen P LubyMahmudur Rahman
Jun 4, 2010·The Journal of General Virology·A S TurmelleC E Rupprecht
Dec 3, 2010·Emerging Infectious Diseases·Sohayati A RahmanUNKNOWN Henipavirus Ecology Research Group
Dec 3, 2010·PLoS Genetics·Aris Katzourakis, Robert J Gifford
Feb 1, 2011·The Journal of Immunology : Official Journal of the American Association of Immunologists·Peng ZhouMichelle L Baker
Aug 26, 2011·Nature·Jan E CaretteThijn R Brummelkamp
Sep 20, 2011·Vector Borne and Zoonotic Diseases·Muhammad Aziz RahmanStephen P Luby
Nov 4, 2011·The American Journal of Tropical Medicine and Hygiene·Kim HalpinUNKNOWN Henipavirus Ecology Research Group
Mar 2, 2012·Journal of Virology·Ann Cogswell-HawkinsonTony Schountz
Aug 11, 2012·PLoS Pathogens·Glenn A MarshLin-Fa Wang
Sep 5, 2013·MBio·Simon J AnthonyW Ian Lipkin
Oct 17, 2013·PLoS Pathogens·Suxiang TongRuben O Donis

❮ Previous
Next ❯

Citations

Jul 24, 2020·The American Journal of Tropical Medicine and Hygiene·David M MorensJeffery K Taubenberger
Sep 25, 2020·MSphere·Ben M HauseJane Christopher-Hennings
Oct 13, 2020·Frontiers in Microbiology·Yuki Furuse, Hitoshi Oshitani
Sep 29, 2020·Transboundary and Emerging Diseases·Saverio PaltrinieriStefania Lauzi
Nov 10, 2020·PLoS Biology·Rebekah C Kading, Tigga Kingston
Dec 29, 2020·Computational and Structural Biotechnology Journal·Christos A Ouzounis
Aug 28, 2020·Cell·David M Morens, Anthony S Fauci
Jan 4, 2021·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Sandrama NadanNicola A Page
Oct 17, 2020·Peptides·Patricia Ribeiro de CarvalhoPatricia Dias Fernandes
Nov 12, 2020·Frontiers in Veterinary Science·Chris Walzer
Feb 16, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Edith DarcissacAnne Lavergne
Feb 12, 2021·Viruses·Suresh V KuchipudiMurugan Subbiah
Feb 21, 2021·Scientific Reports·Rudolf A RömerA Katrine Wallis
Mar 7, 2021·Microorganisms·Paolo CalistriAlessio Lorusso
Feb 24, 2021·Biological Procedures Online·Fateme KhomariElham Bahreini
Mar 4, 2021·Environmental Science and Pollution Research International·Amr El-Sayed, Mohamed Kamel
Mar 3, 2021·Nature Reviews. Immunology·Lin-Fa WangEmma C Teeling
Aug 7, 2020·Travel Medicine and Infectious Disease·Kuldeep DhamaAlfonso J Rodriguez-Morales
Apr 4, 2021·Microorganisms·Roberto J Hermida LorenzoBeatriz Escudero-Pérez
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·José Manuel Pérez de la LastraAntonio Morales-delaNuez
Apr 9, 2021·Nitric Oxide : Biology and Chemistry·Lara M F GuimarãesClaudiana Lameu
Apr 25, 2021·Trends in Microbiology·Celine E SneddenJames O Lloyd-Smith
Apr 27, 2021·International Journal for Parasitology. Parasites and Wildlife·Ajib DiptyanusaTri Baskoro Tunggul Satoto
Apr 19, 2021·Trends in Ecology & Evolution·Willem ProesmansAdam J Vanbergen
May 11, 2021·Reviews in Medical Virology·Aziz Ul-RahmanMuhammad Zubair Shabbir
May 31, 2021·Current Opinion in Virology·Chee Wah TanLin-Fa Wang
Jun 8, 2021·Frontiers in Veterinary Science·Herbert F JelinekHabiba S Alsafar
Jul 3, 2021·Viruses·Itandehui Hernández-AguilarDarío Navarrete-Gutiérrez
Jun 14, 2021·Journal of Comparative Pathology·Shannon G M KirejczykNicole Gottdenker
Jun 23, 2021·Journal of the Indian Institute of Science·Kritika M Garg, Balaji Chattopadhyay
Jul 3, 2021·Viruses·Esen SokulluBenoit Coulombe

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Methods Mentioned

BETA
PCR
glycosylation

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