Bats respond to simulated bacterial infection during the active phase by reducing food intake.

Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
Gabriel MelhadoAriovaldo P da Cruz-Neto

Abstract

Sickness triggers a series of behavioral and physiological processes collectively known as acute phase response (APR). Bats are known as reservoirs of a broad variety of pathogens and the physiological changes resulting from APR activation have been tested predominantly during the resting phase (daytime) in several species exposed to lipopolysaccharide (LPS). In contrast, behavioral consequences of sickness for bats and other wild mammals have received less attention. We examined the physiological and behavioral consequences of APR activation in a fruit-eating bat (Carollia perspicillata) challenged with LPS during the active phase (nighttime). We measured changes in food intake, body mass, body temperature, total white blood cell counts, and the neutrophil/lymphocyte ratio (N/L). No fever and leukocytosis were observed in bats injected with LPS, but food intake decreased, bats lost body mass and their N/L ratio increased. The effect of LPS on daily energy balance is remarkable and, along with the increase in N/L ratio, it is assumed to be beneficial to fight disease. On the basis of our findings and those with other bats, it is probable that the physiological and behavioral components of the immune response to LPS follow circa...Continue Reading

References

Mar 1, 1979·The American Journal of Clinical Nutrition·M J Murray, A B Murray
Jan 1, 1993·Annual Review of Psychology·R Ader, N Cohen
Nov 1, 1996·The Journal of Infectious Diseases·T PollmächerF Holsboer
Sep 18, 1997·Immunology Today·T Wilckens, R De Rijk
Aug 12, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·F I LukerH P Laburn
Mar 12, 2002·Proceedings. Biological Sciences·Staci D BilboRandy J Nelson
Jun 20, 2002·Veterinary Immunology and Immunopathology·R W Johnson
Apr 22, 2003·The American Naturalist·Camille BonneaudGabriele Sorci
Feb 25, 2006·Nature Reviews. Immunology·Carl Nathan
Jul 19, 2006·Clinical Microbiology Reviews·Charles H CalisherTony Schountz
Aug 16, 2008·General and Comparative Endocrinology·T D Siopes, H A Underwood
Mar 30, 2010·The Journal of Experimental Biology·Gary BurnessElinor Tilman-Schindel
May 7, 2010·The Journal of Animal Ecology·John R Speakman, Elzbieta Król
Aug 7, 2012·Zoonoses and Public Health·K Mühldorfer
Feb 9, 2013·Nature Reviews. Immunology·Christoph ScheiermannPaul S Frenette
Sep 14, 2013·The Journal of Experimental Biology·Karin SchneebergerChristian C Voigt
Mar 20, 2014·Physiological and Biochemical Zoology : PBZ·Sandra Sköld-ChiriacDennis Hasselquist
Mar 6, 2015·Memórias do Instituto Oswaldo Cruz·Ricardo Moratelli, Charles H Calisher
Aug 2, 2015·The Journal of Experimental Biology·Sandra Sköld-ChiriacDennis Hasselquist
Sep 4, 2015·Biology Letters·Sebastian StockmaierM Teague O'Mara
Nov 7, 2015·General and Comparative Endocrinology·Elizabeth D Carlton, Gregory E Demas
Nov 26, 2016·Science·Kevin ManAjay Chawla
Dec 17, 2018·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Lucía V Cabrera-MartinezAriovaldo P Cruz-Neto

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Citations

Apr 21, 2021·Annals of the New York Academy of Sciences·Kelsey R MorenoYossi Yovel

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