Bauplan of urmetazoa: basis for genetic complexity of metazoa

International Review of Cytology
Werner E G MüllerIsabel M Müller

Abstract

Sponges were first grouped to the animal-plants or plant-animals then to the Zoophyta or Mesozoa and finally to the Parazoa. Only after the application of molecular biological techniques was it possible to place the Porifera monophyletically with the other metazoan phyla, justifying a unification of all multicellular animals to only one kingdom, the Metazoa. The first strong support came from the discovery that cell-cell and cell-matrix adhesion molecules that were cloned from sponges and were subsequently expressed share a high DNA sequence and protein function similarity with the corresponding molecules of other metazoans. Besides these evolutionary novelties for Metazoa, sponges also have morphogens and transcription factors in common with other metazoan phyla. Surprisingly, even those elements exist in Porifera, which are characteristic for pattern and axis formation. Recent studies showed that epithelial layers of sponges are sealed against the extracellular milieu through tight-junction proteins. The cell culture system from sponges, the primmorphs, was suitable for understanding morphogenetic events. Finally, stem cell marker genes were isolated, which underscored that sponge cells have the capacity to differentiate. In ...Continue Reading

Citations

Aug 6, 2010·Nature·Mansi SrivastavaDaniel S Rokhsar
Jul 31, 2008·Proceedings. Biological Sciences·Jaap A KaandorpWerner E G Müller
Jul 3, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Douglas H Erwin
Jun 8, 2007·Microbiology and Molecular Biology Reviews : MMBR·Michael W TaylorMichael Wagner
Dec 15, 2007·Biology Direct·Joseph F Ryan, Andreas D Baxevanis
Jun 19, 2008·Zoological Science·Junko IshijimaYoichi Matsuda
Mar 27, 2007·Micron : the International Research and Review Journal for Microscopy·Matthias WiensWerner E G Müller
Jun 30, 2006·Seminars in Cell & Developmental Biology·Werner E G Müller
Aug 12, 2005·Annals of the New York Academy of Sciences·Nanette H Bishopric
Aug 8, 2013·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Werner E G MüllerXiaohong Wang
Jun 24, 2005·Nature·Helen Pilcher
Nov 9, 2007·Chemical Communications : Chem Comm·Mohammed Ibrahim ShukoorWolfgang Tremel
May 24, 2008·Natural Product Reports·Heinz C SchröderWerner E G Müller
Jan 21, 2009·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Alexander V EreskovskyJean Vacelet
Jun 11, 2005·Cell and Tissue Research·Werner E G MüllerHeinz C Schröder
Sep 1, 2009·Integrative Zoology·Emmanuelle RenardAlexander V Ereskovsky
Dec 13, 2005·Nature Reviews. Genetics·Jordi Garcia-Fernàndez
Dec 13, 2005·Nature Reviews. Genetics·Mark Q Martindale
Mar 6, 2007·Journal of Molecular Evolution·Helena CetkovicVera Gamulin
Sep 24, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Xiaohong WangWerner E G Müller
Mar 12, 2013·Integrative and Comparative Biology·Werner E G MüllerXiaohong Wang

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