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Bayesian inference of spatial organizations of chromosomes

PLoS Computational Biology

Feb 6, 2013

Ming HuJun S Liu

Abstract

Knowledge of spatial chromosomal organizations is critical for the study of transcriptional regulation and other nuclear processes in the cell. Recently, chromosome conformation capture (3C) based technologies, such as Hi-C and TCC, have been developed to provide a genome-wide, three-di...read more

Mentioned in this Paper

RNA Polymerase II
Chromosomes, Human, Pair 1
Chromosome Structures
Genome
Nuclear Lamina
Promoter
Chromosomes, Human
Deoxyribonuclease HindIII
Transcription Elongation
Etiology
8
239
Paper Details
References
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Bayesian inference of spatial organizations of chromosomes

PLoS Computational Biology

Feb 6, 2013

Ming HuJun S Liu

PMID: 23382666

DOI: 10.1371/journal.pcbi.1002893

Abstract

Knowledge of spatial chromosomal organizations is critical for the study of transcriptional regulation and other nuclear processes in the cell. Recently, chromosome conformation capture (3C) based technologies, such as Hi-C and TCC, have been developed to provide a genome-wide, three-di...read more

Mentioned in this Paper

RNA Polymerase II
Chromosomes, Human, Pair 1
Chromosome Structures
Genome
Nuclear Lamina
Promoter
Chromosomes, Human
Deoxyribonuclease HindIII
Transcription Elongation
Etiology
8
239

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Eukaryotic RNA Polymerase II (Keystone)

RNA polymerase II (RNAP II) is a 550 kDa multiprotein complex composed of 12 subunits. Here is the latest research on RNAP II and its role it regulating transcription and transcription-coupled recombination repair.

Epigenetics

Epigenetics is the study of heritable changes in gene expression that do not involve alteration of the DNA sequence. Here is the latest research.

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Paper Details
References
  • References41
  • Citations59
12345
  • References41
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12345...
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