Bayesian methods for genomic breeding value estimation

Yi chuan = Hereditas
Chonglong WangQin Zhang

Abstract

Estimation of genomic breeding values is the key step in genomic selection. The successful application of genomic selection depends on the accuracy of genomic estimated breeding values, which is mostly determined by the estimation method. Bayes-type and BLUP-type methods are the two main methods which have been widely studied and used. Here, we systematically introduce the currently proposed Bayesian methods, and summarize their effectiveness and improvements. Results from both simulated and real data showed that the accuracies of Bayesian methods are higher than those of BLUP methods, especially for the traits which are influenced by QTL with large effect. Because the theories and computation of Bayesian methods are relatively complicated, their use in practical breeding is less common than BLUP methods. However, with the development of fast algorithms and the improvement of computer hardware, the computational problem of Bayesian methods is expected to be solved. In addition, further studies on the genetic architecture of traits will provide Bayesian methods more accurate prior information, which will make their advantage in accuracy of genomic estimated breeding values more prominent. Therefore, the application of Bayesian m...Continue Reading

Related Concepts

Bayesian Prediction
Breeding
Genomics
Breeding
Genome
Selection, Genetic
Cell Type
Simulation
Computed (Procedure)
Study

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