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Bbeta15-42 (FX06) reduces pulmonary, myocardial, liver, and small intestine damage in a pig model of hemorrhagic shock and reperfusion

Critical Care Medicine

Dec 31, 2008

J P RoesnerKai Zacharowski

Abstract

The fibrin-derived peptide Bbeta15-42 (also called FX06) has been shown to reduce myocardial infarct size following ischemia/reperfusion. Hemorrhagic shock (HS) followed by volume resuscitation represents a similar scenario, whereby a whole organism is vulnerable to reperfusion injury. ...read more

Mentioned in this Paper

Arterial Pulse Pressure
Buffers
Ischemia
Reperfusion Injury
Fibrin Measurement
Circulatory System
Lung
Blood Vessel
Small Intestinal Wall Tissue
Neutrophils as Percentage of Blood Leukocytes (Lab Test)
Paper Details
References
  • References41
  • Citations11
12345
  • References41
  • Citations11
12

Bbeta15-42 (FX06) reduces pulmonary, myocardial, liver, and small intestine damage in a pig model of hemorrhagic shock and reperfusion

Critical Care Medicine

Dec 31, 2008

J P RoesnerKai Zacharowski

PMID: 19114899

DOI: 10.1097/ccm.0b013e3181959a12

Abstract

The fibrin-derived peptide Bbeta15-42 (also called FX06) has been shown to reduce myocardial infarct size following ischemia/reperfusion. Hemorrhagic shock (HS) followed by volume resuscitation represents a similar scenario, whereby a whole organism is vulnerable to reperfusion injury. ...read more

Mentioned in this Paper

Arterial Pulse Pressure
Buffers
Ischemia
Reperfusion Injury
Fibrin Measurement
Circulatory System
Lung
Blood Vessel
Small Intestinal Wall Tissue
Neutrophils as Percentage of Blood Leukocytes (Lab Test)

Related Papers

Paper Details
References
  • References41
  • Citations11
12345
  • References41
  • Citations11
12
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