Beat-to-beat electrocardiographic analysis of ventricular repolarization variability in patients after myocardial infarction

Journal of Electrocardiology
P D Arini, E R Valverde

Abstract

Several studies have shown that the beat-to-beat variability of ventricular repolarization, which can be computed by T-wave spectral variance (TSV) index, constitutes a marker of cardiac risk. Moreover, the fact that properties of action potential duration are altered during the healing (days, weeks) and healed (months) infarct stages, have been reported. However, no data exist regarding the influence of the time elapsed after myocardial infarction (MI) on modulation of the beat-to-beat ventricular repolarization variability. In the present work we have evaluated TSV index during healing and healed stages of MI using 12 standard ECG leads. The ECG of control or healthy subjects (n = 49) and the ECGs in patients after MI (n = 38), one within the first seven days (MI7) and the other after 60 days (MI60) of cardiac infarction, have been analyzed. We have considered the preferential ECG leads as those leads in which TSV index have presented a relative change greater than 10 in MI7 respect to control. Results indicate that TSV index have shown a significant increase (p < 0.0005) in I, II, aVR, aVF, V3, V4, V5 and V6 leads in healing phase of MI (MI7) with respect to control. Further, in the healed phase of MI (MI60), the TSV index t...Continue Reading

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Citations

Mar 5, 2016·Journal of Electrocardiology·Lennart Bergfeldt
Sep 8, 2016·Journal of Electrocardiology·Jan Němec

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