Nov 1, 1975

Beclomethasone dipropionate aerosol in treatment of hay fever in children

Archives of Disease in Childhood
P PrahlN Mygind

Abstract

Eighteen children suffering from hay fever were treated with intra-nasal beclomethasone dipropionate (400 mug/day) and an identical placebo aerosol in a double-blind cross-over trial. 17 of the children preferred the intranasal beclomethasone dipropionate, one had no preference, none preferred the placebo. The effect on the nasal symptoms was impressive. Symptom scores decreased, on average, to 12% and the number of antihistamine tablets taken to 18% of the pretreatment amount. Some beneficial effect on eye symptoms was also discernible, possibly due to an indirect influence from the nasal mucosa via the nasolacrimal reflex. Adrenal function was not affected. It was concluded that 400 mug beclomethasone dipropionate given intranasally daily for some weeks is an effective and safe treatment for hay fever in children.

Mentioned in this Paper

Antihistamine [EPC]
Antihistamines, Classical
Adrenal Glands
Benzhydryl Compounds
Structure of Mucous Membrane of Nose
Hay Fever
Aerosol Dose Form
Antihistamine brand of Diphenhydramine
Bronchocort
Clinical Trials

About this Paper

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