PMID: 2110Nov 1, 1975

Beclomethasone dipropionate aerosol in treatment of hay fever in children

Archives of Disease in Childhood
P PrahlN Mygind

Abstract

Eighteen children suffering from hay fever were treated with intra-nasal beclomethasone dipropionate (400 mug/day) and an identical placebo aerosol in a double-blind cross-over trial. 17 of the children preferred the intranasal beclomethasone dipropionate, one had no preference, none preferred the placebo. The effect on the nasal symptoms was impressive. Symptom scores decreased, on average, to 12% and the number of antihistamine tablets taken to 18% of the pretreatment amount. Some beneficial effect on eye symptoms was also discernible, possibly due to an indirect influence from the nasal mucosa via the nasolacrimal reflex. Adrenal function was not affected. It was concluded that 400 mug beclomethasone dipropionate given intranasally daily for some weeks is an effective and safe treatment for hay fever in children.

References

Jan 1, 1972·Current Medical Research and Opinion·S S ChatterjeeA G Butler
Aug 1, 1974·Archives of Disease in Childhood·S Godfrey, P König
Feb 8, 1969·British Medical Journal·M A GandertonA W Frankland
May 1, 1965·The Journal of Allergy·P S Norman, W L Winkenwerder

Citations

Jul 10, 1999·The Journal of Allergy and Clinical Immunology·E O MeltzerK B Nolop
Apr 23, 2008·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·R W Weber
Mar 12, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·J M TracyD W Goetz
Jan 1, 1977·Clinical Allergy·N MygindJ Thomsen
Jun 1, 1977·Archives of Disease in Childhood·S C Shore, E G Weinberg
Jul 14, 1979·British Medical Journal·J K Sarsfield, G E Thomson
Jan 13, 2015·Allergology International : Official Journal of the Japanese Society of Allergology·Kimihiro OkuboMasaki Komatsubara
Jul 25, 2014·Allergology International : Official Journal of the Japanese Society of Allergology·Kimihiro OkuboMasaki Komatsubara
Oct 1, 1982·Clinical Otolaryngology and Allied Sciences·N Mygind
Sep 25, 1999·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·O D Wolthers, J W Honour
Sep 5, 2008·Current Opinion in Allergy and Clinical Immunology·Catherine Origlieri, Leonard Bielory

Related Concepts

Aerosol Dose Form
Bronchocort
Benzhydryl Compounds
Clinical Trials
Eye Manifestations
Hay Fever
Antihistamines, Classical
Urbason
Placebos

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