Abstract
The main aim of the present report is to study the pattern of distribution of cervical metastasis in buccal mucosa cancer and to discuss the various therapeutic options available. Fifty-three patients with squamous cell carcinoma of the buccal mucosa treated with tumorectomy and selective neck dissection were included in the study. We also studied the relationship between specific pathological features and overall survival. Level Ib was the most affected level, followed by level IIa. T stage, N stage, N involvement tumor thickness, extracapsular spread (ECS), and vascular invasion were associated with poorer outcomes regarding overall survival ( p < 0.001). Carcinoma of the buccal mucosa should be treated aggressively from the early stages. A large tumorectomy of the primary tumor is required to reduce the number of local recurrences. Moreover, we recommend performing a supraomohyoid neck dissection even in cT1N0 if there is a suspicion that the tumor thickness may be greater than 0.4 cm. The high risk of local recurrence obliges protection of the neck from a future cervical recurrence even in T1 small tumors. This could reduce the risk of cervical involvement during the follow-up and improve overall survival rates.
References
Apr 1, 1979·Archives of Otolaryngology·J W VegersI van der Waal
Jan 1, 1997·Head & Neck·R M ByersP Wolf
Aug 1, 1997·Head & Neck·J J Manni
Sep 1, 1997·Head & Neck·F M FangD T Huang
Mar 4, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·S E StromeR M Esclamado
Nov 20, 2001·American Journal of Otolaryngology·E SieczkaW Hicks
Jul 16, 2002·Archives of Otolaryngology--head & Neck Surgery·K Thomas RobbinsUNKNOWN American Academy of Otolaryngology--Head and Neck Surgery
Mar 27, 2003·Head & Neck·Eduardo M DiazDouglas M Sorensen
Sep 4, 2003·Head & Neck·St-John CreanM J Fardy
Oct 7, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Anthony SparanoRandal Weber
Oct 4, 2005·Head & Neck·Chun-Shu LinWeng-Yoon Shum
Jul 11, 2006·The Laryngoscope·Young Chang LimEun Chang Choi
Nov 15, 2006·Head & Neck·Ana CapoteLuis Naval
Jun 9, 2009·Oral Diseases·S ErgunH Tanyeri
Mar 12, 2011·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Oliver C ThieleKolja Freier
Sep 18, 2012·Otolaryngologic Clinics of North America·Marcus M Monroe, Neil D Gross
Dec 21, 2012·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·N P TrivediM A Kuriakose
Feb 1, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Zhien FengChuan Bin Guo
Jan 7, 2015·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Mar 11, 2016·Indian Journal of Cancer·N P TrivediM A Kuriakose
Sep 25, 2016·Oral and Maxillofacial Surgery·Faisal IdreesDeepak Agrawal
Dec 3, 2016·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Takumi HasegawaTakahide Komori
Dec 10, 2016·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Keyvan SaghebChristian Walter
Citations
Aug 25, 2020·Journal of Surgical Oncology·Xiaoshan WuFeng Guo
Jun 11, 2020·BMC Cancer·Qigen FangYuanyuan Dong
Jul 29, 2020·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Leandros V VassiliouNicholas Kalavrezos