Behavioral Screening of Alcohol Effects and Individual Differences in Zebrafish (Danio rerio).

Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism
Heloysa Araujo-SilvaAna Carolina Luchiari

Abstract

To better understand the individual differences that make up a population, this study aimed to evaluate the effects of different alcoholic concentrations on the behavioral profiles of zebrafish (Danio rerio). For this purpose, adult animals were separated into two behavioral profiles: bold and shy, according to the emergence order. Bold and shy fish were individually tested for exploration after exposure to the drug. Acute exposure treatments were alcohol 0.00, 0.10, 0.25 and 0.50%. The behavioral parameters evaluated were speed while moving, maximum speed, total distance traveled and distance from the bottom of the tank. For the groups that did not receive alcohol, bold animals showed higher speed while moving. Shy 0.00% and shy 0.10% had the highest maximum speed compared with other concentrations and profiles. For the distance from the bottom tank, our results showed that the increase induced by the low acute dose (0.10%) was observed for both profiles. Our results corroborate with previous findings that alcohol affects the behavioral profiles of zebrafish differently, with bold animals apparently more resistant to these changes.

References

May 1, 1992·Trends in Pharmacological Sciences·H H Samson, R A Harris
Jul 1, 1996·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·P L Hoffman, B Tabakoff
Dec 2, 1999·Neuroscience and Biobehavioral Reviews·J M KoolhaasH J Blokhuis
Feb 13, 2001·Pharmacology, Biochemistry, and Behavior·R GerlaiA Rosenthal
Feb 25, 2005·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Marcos ZaleskiTadeu Lemos
Jul 5, 2005·Nature Reviews. Genetics·David GoldmanFrancesca Ducci
Jul 1, 2006·Methods : a Companion to Methods in Enzymology·Jovica Ninkovic, Laure Bally-Cuif
Oct 20, 2006·Physiology & Behavior·Edward D LevinDaniel T Cerutti
Dec 14, 2006·Proceedings. Biological Sciences·Ashley J FrostLynne U Sneddon
Jan 2, 2007·Pharmacology, Biochemistry, and Behavior·Robert GerlaiRachel Blaser
Oct 5, 2007·Brain, Behavior and Evolution·Jaap M KoolhaasKees van Reenen
Jun 23, 2009·Behavioural Brain Research·Rupert J EganAllan V Kalueff
Sep 30, 2009·Current Psychiatry Reports·David StaceyGunter Schumann
Apr 13, 2010·Frontiers in Neuroendocrinology·J M KoolhaasB Buwalda
Aug 4, 2010·BMC Neuroscience·William Norton, Laure Bally-Cuif
Nov 17, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Caroline M CoppensJaap M Koolhaas
Dec 3, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Adam StewartAllan V Kalueff
Nov 1, 1994·Trends in Ecology & Evolution·D Sloan WilsonT Dearstyne
Jan 18, 2011·Progress in Neuro-psychopharmacology & Biological Psychiatry·Caio MaximinoAnderson Manoel Herculano
Mar 16, 2011·Proceedings of the National Academy of Sciences of the United States of America·Nicholas A NasrallahIlene L Bernstein
May 14, 2011·Neuroscience and Biobehavioral Reviews·Simona Cabib, Stefano Puglisi-Allegra
Aug 23, 2011·PloS One·S Josefin DahlbomSvante Winberg
Sep 25, 2012·Critical Care Clinics·Richard W CarlsonShivaramaiah Shashikumar
Dec 12, 2012·Behavioural Brain Research·Noam MillerRobert Gerlai
Apr 18, 2013·Zebrafish·Allan V KalueffUNKNOWN Zebrafish Neuroscience Research Consortium
Jun 13, 2013·Behavioural Brain Research·Steven Tran, Robert Gerlai
Nov 8, 2013·The Journal of Endocrinology·Christian TudoracheHans Slabbekoorn
Jan 15, 2014·Trends in Pharmacological Sciences·Allan V KalueffRobert Gerlai
Apr 1, 2014·Progress in Neuro-psychopharmacology & Biological Psychiatry·Diana M Chacon, Ana C Luchiari
May 14, 2014·Alcoholism, Clinical and Experimental Research·Fabrizio LaduMaurizio Porfiri
Jul 22, 2014·Addictive Behaviors·Matthew J Gullo, Marc N Potenza
Aug 1, 2014·PloS One·Caio MaximinoAnderson Manoel Herculano
Aug 28, 2016·Behavioural Processes·S L WhiteV A Braithwaite
Sep 21, 2016·Animal Cognition·Jaquelinne Pinheiro-da-SilvaAna Carolina Luchiari
Jul 18, 2017·Zebrafish·Ricardo Rodrigues AmorimAna Carolina Luchiari
Jun 8, 2018·PloS One·Heloysa Araujo-SilvaAna C Luchiari
Aug 10, 2019·Frontiers in Behavioral Neuroscience·Maria Elisa Leite-FerreiraAna Carolina Luchiari

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved