PMID: 9427091Jan 14, 1998Paper

Behaviour changes in dementia. 2: Are there behavioural syndromes?

International Journal of Geriatric Psychiatry
T HopeR Jacoby

Abstract

To establish whether robust behavioural 'syndromes' can be identified from among the widely heterogeneous behavioural changes which occur in dementia. Longitudinal, prospective study with follow-up at 4 and 8 months. Community settings in Oxfordshire, UK. 97 elderly people with a diagnosis of Alzheimer's disease or vascular dementia (in many cases confirmed by postmortem examination) and who were living at home with a carer. Each subject's behaviour was assessed in detail at each interview using the Present Behavioural Examination to assess subject's behaviour over the preceding 4 weeks. Seventeen key behaviour items which were both common and clinically important were selected for further analysis. Three syndromes were identified: (a) overactivity (walking more, walking aimlessly, trailing the carer or checking where the carer was); (b) aggressive behaviour (physical aggression, aggressive resistance, verbal aggression); (c) psychosis (anxiety, persecutory ideas and hallucinations). The same syndromes were found using data collected at three different time points and by using a variety of statistical techniques, confirming their robustness. Overactivity, aggressive behaviour and psychosis form three distinct behavioural syndro...Continue Reading

References

Jan 1, 1992·International Psychogeriatrics·J Cohen-MansfieldP Werner

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Citations

May 29, 2008·Journal of Neural Transmission·Mitchell K P LaiPaul T Francis
Nov 13, 2004·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Sergio E StarksteinAgustina Cao
Oct 5, 2010·Neuroreport·Mitchell K P LaiMargaret M Esiri
Jul 6, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·D AarslandJ L Cummings
Nov 8, 2007·Dementia and Geriatric Cognitive Disorders·Pauline AaltenPhilippe H Robert
May 23, 2014·The Nursing Clinics of North America·Rebecca J RileyKathleen C Buckwalter
Apr 10, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Joan Vilalta-FranchJosep Garre-Olmo
Nov 4, 2011·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Jeremy KoppelBlaine S Greenwald
Mar 12, 2010·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Joan Vilalta-FranchJosep Garre-Olmo
Oct 13, 2009·Journal of the Neurological Sciences·Shirley W TsangMitchell K Lai
Aug 30, 2008·Journal of the American Medical Directors Association·Karan S KvernoPeter V Rabins
Jul 4, 2006·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Joan Vilalta-FranchRegina Feijóo-Lorza
Feb 22, 2012·International Journal of Alzheimer's Disease·Jason A Staal
Aug 5, 2016·Geriatrics & Gerontology International·Michele TorrisiRocco Salvatore Calabrò
Aug 31, 2016·International Psychogeriatrics·Janny HoSytse U Zuidema
Jul 2, 2008·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Saw-Myo TunChristopher C Colenda
Nov 24, 2004·American Journal of Alzheimer's Disease and Other Dementias·Erin L Cidboy
Dec 19, 2001·International Journal of Geriatric Psychiatry·B Lawlor, S N Bhriain
Aug 10, 1999·International Journal of Geriatric Psychiatry·J KeeneC J Ware
Nov 18, 2003·International Journal of Geriatric Psychiatry·Dawn PotkinsMarisa Margallo-Lana
Apr 16, 2014·Dementia and Geriatric Cognitive Disorders·Kenji TagaiKazuhiko Nakayama
Apr 23, 2003·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Clive HolmesSimon Lovestone
May 8, 2002·International Journal of Geriatric Psychiatry·Michal Schnaider BeeriShlomo Noy
Aug 2, 2003·International Journal of Geriatric Psychiatry·Jos F M de JongheMiel W Ribbe
Oct 14, 2004·International Journal of Geriatric Psychiatry·A MirakhurA P Passmore
Sep 7, 2006·International Journal of Geriatric Psychiatry·M SteinbergC G Lyketsos
Jul 4, 2007·International Journal of Geriatric Psychiatry·Martin SteinbergUNKNOWN Cache County Investigators
Jul 16, 2005·International Journal of Geriatric Psychiatry·Adrienne P de Jonghe-RouleauJos F M de Jonghe
Jul 2, 2002·The British Journal of Psychiatry : the Journal of Mental Science·J WolstenholmeT Hope
Feb 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·N TunstallS Lovestone
Apr 22, 1999·The British Journal of Psychiatry : the Journal of Mental Science·T HopeR McShane
Feb 5, 2014·Cognitive, Affective & Behavioral Neuroscience·Susanna PietropaoloBenjamin K Yee
Jul 18, 2008·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Jeffrey L CummingsDaniel Kaufer
Sep 17, 2016·JBI Database of Systematic Reviews and Implementation Reports·Benjamin FoxChristine Neville
Jan 22, 2005·International Journal of Geriatric Psychiatry·Daniel SchreinzerPeter Fischer
Feb 17, 2001·International Journal of Geriatric Psychiatry·E Moniz-CookK Richards

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