PMID: 9534839Apr 16, 1998Paper

Behaviour phenotype for Down's syndrome

The British Journal of Psychiatry : the Journal of Mental Science
R A CollacottC McGrother

Abstract

For more than a century, the idea of particular personality/behavioural characteristics being associated with people with Down's syndrome has been explored, but with inconclusive results. The Disability Assessment Schedule was used to ascertain the behavioural profiles of 360 adults with Down's syndrome and 1829 adults with learning disabilities of other aetiologies, who were the whole identified population within a defined geographical area. Comparison was made between the two total groups and additionally for the subgroups aged < 35 years and aged > or = 35 years. Comparison was also made with regards to cluster analysis findings. Despite an equal age and developmental quotient, the Down's syndrome group were less likely to demonstrate maladaptive behaviours. The behaviour characteristics of the adults with Down's syndrome remained constant in the younger and older age groups. Cluster analysis demonstrated adults with Down's syndrome to have an increased prevalence in cluster groupings with lower rates of maladaptive behaviours. This study confirms there to be a behaviour phenotype among adults with Down's syndrome. The reasons for this (e.g. genetic/psychological/social) require further research. Such research may establish ...Continue Reading

References

Nov 1, 1992·The British Journal of Psychiatry : the Journal of Mental Science·R A CollacottC McGrother
Nov 1, 1992·The British Journal of Psychiatry : the Journal of Mental Science·R A Collacott
May 1, 1986·Psychological Medicine·C Oliver, A J Holland
Aug 1, 1986·The British Journal of Psychiatry : the Journal of Mental Science·A Gath, D Gumley
Aug 1, 1996·The British Journal of Psychiatry : the Journal of Mental Science·S SmithC McGrother

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Citations

Oct 24, 2001·Indian Journal of Pediatrics·V Grech
Mar 4, 2008·Journal of Autism and Developmental Disorders·Craig A MelvilleDipali Mantry
Jul 11, 2003·Lancet·André Strydom
Aug 31, 1999·Journal of Intellectual Disability Research : JIDR·A YorkP Sedgwick
Mar 11, 2000·Journal of Intellectual Disability Research : JIDR·J Kerbeshian, L Burd
Nov 18, 2000·Journal of Intellectual Disability Research : JIDR·M Ghaziuddin
Oct 2, 2002·Journal of Intellectual Disability Research : JIDR·E M DykensB H King
Feb 1, 2003·Journal of Intellectual Disability Research : JIDR·J A TsiourisP Sturmey
Feb 29, 2008·Harvard Review of Psychiatry·Claire Brickell, Kerim Munir
Jun 19, 2009·Current Opinion in Psychiatry·Sally-Ann Cooper, Rohan van der Speck
May 14, 2014·Journal of Neurodevelopmental Disorders·Kate E EdenChris Oliver
Apr 30, 2010·Topics in Language Disorders·Gary E MartinJoanne E Roberts
Nov 26, 2009·American Journal on Intellectual and Developmental Disabilities·Jane PettyChris Oliver
Nov 3, 2010·Research in Developmental Disabilities·Fay Cook, Chris Oliver
Sep 8, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Alain D DekkerPeter P De Deyn
Jan 17, 2008·Journal of Intellectual Disability Research : JIDR·D MantryA Jackson
Mar 2, 2006·Journal of Intellectual Disability Research : JIDR·F TyrerC Hollin
Sep 12, 2007·Journal of Intellectual Disability Research : JIDR·S DebL Prior
Jun 15, 2007·Child and Adolescent Psychiatric Clinics of North America·Carl Feinstein, Sonia Singh
Mar 7, 2014·Research in Developmental Disabilities·Laurie Powis, Chris Oliver
Oct 16, 2007·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Mohammed Rachidi, Carmela Lopes
May 14, 2017·Journal of Autism and Developmental Disorders·Lucy Wilde, Chris Oliver
Sep 16, 2008·The Journal of Nervous and Mental Disease·Sheena JonesJillian Morrison
Jul 19, 2000·Mental Retardation and Developmental Disabilities Research Reviews·R S Chapman, L J Hesketh
Nov 5, 1999·Journal of Intellectual Disability Research : JIDR·M P CosgraveB A Lawlor
Jun 18, 2020·Molecular Autism·Alejandro López-TobónGiuseppe Testa

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