Behavioural actions of neurohypophysial peptides

Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character
D De Wied

Abstract

The neurohypophysial hormones vasopressin and oxytocin modulate memory processes. Vasopressin facilitates while oxytocin attenuates memory consolidation and retrieval. These influences are located in different regions of the molecules. Thus, the neurohypophysial hormones act as precursor molecules for neuropeptides involved in memory processes. The covalent ring structures of both vasopressin and oxytocin mainly affect consolidation, the linear parts, retrieval processes, while nearly the whole oxytocin or vasopressin molecule is needed for attenuation of consolidation and retrieval. Regional studies by microdissection techniques in combination with a sensitive radioenzymatic catecholalmine assay, indicate that vasopressin modulates memory processes by modulation of neurotransmission in distinct catecholamine systems. Recent experiments suggest that the influence of vasopressin on memory consolidation is mediated by the dorsal noradrenergic bundle via terminal regions of this bundle. Studies on the conversion of oxytocin in synaptosomal plasma membrane preparations of rat limbic brain suggest the possible generation of fragments with specific effects on memory processes. Regional differences in enzyme activity further substanti...Continue Reading

Citations

Apr 1, 1994·Integrative Physiological and Behavioral Science : the Official Journal of the Pavlovian Society·D A Powell
Oct 14, 1983·European Journal of Pharmacology·J P BurbachD De Wied
Nov 19, 1985·European Journal of Pharmacology·P MontastrucJ L Montastruc
Mar 26, 1985·European Journal of Pharmacology·E R De KloetM Terlou
Nov 4, 1986·European Journal of Pharmacology·A ArgiolasG L Gessa
Oct 5, 1987·Life Sciences·R Arletti, A Bertolini
Jan 1, 1983·Physiology & Behavior·G N Brito
Dec 1, 1990·Physiology & Behavior·R ArlettiA Bertolini
Feb 1, 1985·Pharmacology, Biochemistry, and Behavior·R Hamburger-Bar, M E Newman
Dec 1, 1986·Pharmacology, Biochemistry, and Behavior·O J Gaffori, D De Wied
Aug 1, 1982·Psychiatry Research·W H BerrettiniE S Gershon
Jan 1, 1989·Brain Research. Developmental Brain Research·G AlmazanH H Zingg
Oct 27, 1995·Brain Research. Developmental Brain Research·J Iqbal, C D Jacobson
Jan 1, 1988·Peptides·J A StiversJ N Crawley
Jan 1, 1989·Peptides·R ArlettiA Bertolini
Jan 1, 1985·Neurobiology of Aging·C A PeabodyJ R Tinklenberg
Jan 1, 1986·Progress in Neuro-psychopharmacology & Biological Psychiatry·R F De Estable-PuigC Radouco-Thomas
Jan 1, 1986·Progress in Neuro-psychopharmacology & Biological Psychiatry·L E Hollister
Jan 1, 1986·Progress in Neuro-psychopharmacology & Biological Psychiatry·P Kragh-SørensenK Steffensen
Jan 1, 1988·Progress in Neuro-psychopharmacology & Biological Psychiatry·M A Demitrack, P W Gold
Apr 16, 1993·Neuroscience Letters·J D StoehrW G North
Jan 1, 1985·Psychoneuroendocrinology·O Gaffori, D de Wied
Jan 3, 1981·Lancet·A M StreeterM T Pheils
Aug 1, 1997·Psychoneuroendocrinology·I Liberzon, E A Young
Nov 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M MühlethalerJ J Dreifuss
Sep 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·J S JenkinsA K Coughlan
Jan 1, 2013·ISRN Neuroscience·Hai-Peng YangStephani C Wang

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