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Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice

Nature

Oct 26, 1995

L HeinB K Kobilka

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Abstract

Angiotensin II, a potent regulator of blood pressure and of water and electrolyte balance, binds to two different G-protein-coupled receptors. The type-1 receptor (AT1) mediates the vasopressive and aldosterone-secreting effects of angiotensin II, but the function of the type-2 receptor...read more

Mentioned in this Paper

Behavior, Animal
Cardiovascular System
Diastolic Blood Pressure
Embryonic and Fetal Development
Ren1
Angiotensin II, Val(5)-
Mice, Knockout
Angiotensin Receptor
Vasoconstrictor Agents
Renin-angiotensin System
74
1
Paper Details
References
  • References23
  • Citations415
123
  • References23
  • Citations415
12345...

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Proceedings of the National Academy of Sciences of the United States of America

Regulation of blood pressure by the type 1A angiotensin II receptor gene

Proceedings of the National Academy of Sciences of the United States of AmericaApril 11, 1995
M ItoT M Coffman
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Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice

Nature

Oct 26, 1995

L HeinB K Kobilka

PMID: 7477266

DOI: 10.1038/377744a0

Abstract

Angiotensin II, a potent regulator of blood pressure and of water and electrolyte balance, binds to two different G-protein-coupled receptors. The type-1 receptor (AT1) mediates the vasopressive and aldosterone-secreting effects of angiotensin II, but the function of the type-2 receptor...read more

Mentioned in this Paper

Behavior, Animal
Cardiovascular System
Diastolic Blood Pressure
Embryonic and Fetal Development
Ren1
Angiotensin II, Val(5)-
Mice, Knockout
Angiotensin Receptor
Vasoconstrictor Agents
Renin-angiotensin System
74
1

Feeds With Similar Papers

Stanford Department of Genetics

Find the latest research from the Stanford Medicine Department of Genetics here.

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Regulation of blood pressure by the type 1A angiotensin II receptor gene

Proceedings of the National Academy of Sciences of the United States of AmericaApril 11, 1995
M ItoT M Coffman
Paper Details
References
  • References23
  • Citations415
123
  • References23
  • Citations415
12345...

Download from

Publisher
PubMed
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