Beneficial effect of low-dose peritonsillar injection of lidocaine-adrenaline before tonsillectomy. A placebo-controlled clinical trial

Auris, Nasus, Larynx
Waldemar Trolle SørensenPer Bonding

Abstract

Most studies investigating the effect of preincisional injection of local anaesthetic with adrenaline in tonsillectomy have used rather large doses and an inter-individual study design. They are inconclusive regarding the effect on post-tonsillectomy pain but have shown that the peroperative blood loss is reduced. However, side effects to high adrenaline doses are common. In the present study, the effect of injecting a small dose of lidocaine-adrenaline was investigated by using an intra-individual study design. In this randomised double-blind study 52 patients (33 women and 19 men) received unilateral preincisional injection of 3-ml lidocaine-adrenaline before tonsillectomy. the difference in blood loss was highly significant with a more than 50% reduction in peroperative blood loss in the infiltrated side. Time to achieve haemostasis for one tonsil side was reduced from 6.0 to 4.0 min. No side effects were observed. At the operation day (mean 4.9 h after operation), the visual analogue scale for pain at the side infiltrated with local anaesthetics was 2.78 compared to 4.00 in the control side (P=0.05). Low-dose injection of lidocaine-adrenaline before tonsillectomy reduces blood loss and has a small but significant beneficial...Continue Reading

References

Nov 1, 1980·The Journal of Laryngology and Otology·T A Boliston, J J Upton
Sep 1, 1995·British Journal of Anaesthesia·K E KnudsenJ B Dahl
Apr 10, 1999·Clinical Otolaryngology and Allied Sciences·W T SørensenP Bonding
Jun 25, 1999·Acta Oto-laryngologica·S H NordahlH J Breidablikk

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Citations

May 12, 2005·International Journal of Pediatric Otorhinolaryngology·E EgeliO Ozturk
Jan 23, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Klaus StelterHjalmar Hagedorn
Jan 14, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Klaus StelterMartin Canis
Nov 6, 2008·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·J Grainger, N Saravanappa
Jul 11, 2012·International Journal of Pediatric Otorhinolaryngology·Julide ErgilIstemihan Akin
Nov 27, 2014·The Annals of Otology, Rhinology, and Laryngology·Craig S DerkayLaura Stone
Apr 16, 2020·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Darren YapRam Moorthy

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