Beneficial Effect of Virgin Coconut Oil on Alloxan-Induced Diabetes and Microbiota Composition in Rats

Plant Foods for Human Nutrition
Sinisa DjurasevicDragana Mitic-Culafic

Abstract

The gut microbiota is composed of a diverse population of obligate and facultative anaerobic microorganisms which are shown to influence host metabolism and immune homeostasis. This study investigated the effects of virgin coconut oil on the weekly fasting glycaemia, daily food and water intake and weekly body mass gain over 16 weeks, as well as the changes in composition of gut microbiota in both non-diabetic and alloxan-induced diabetic rats. Although the intake of virgin coconut oil did not decrease the diabetes-induced hyperglycemia, it affected the secondary parameters, such as food and water intake and average body mass gain. Furthermore, its potential to positively affect the fecal microbiome was proved, since it significantly increased the abundance of probiotic bacteria, such as Lactobacillus, Allobaculum and Bifidobacterium species.

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Citations

Jun 12, 2020·International Journal of Molecular Sciences·David Johane MachateArnildo Pott
Nov 5, 2019·Frontiers in Nutrition·Jananee MuralidharanJordi Salas-Salvadó
Dec 4, 2019·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Jing LengJinghua Peng
Jan 12, 2021·Case Reports in Endocrinology·Samar Malaeb, Christopher Spoke
Apr 3, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Siniša ĐuraševićZoran Todorović
Mar 12, 2021·Advances in Nutrition·Kirsten BerdingJohn F Cryan
Jul 3, 2021·Antioxidants·Laura BordoniRosita Gabbianelli
Aug 7, 2021·Saudi Journal of Biological Sciences·Karemah A Alatawi, Fawzia A Alshubaily

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