Beneficial effects of varicocele embolization on semen parameters

Basic and Clinical Andrology
Julie PrasivoravongJean-Marc Rigot

Abstract

The value of varicocele repair and the latter's impact on semen parameters are still subject to debate. We analyse changes over time in initially abnormal sperm parameters and serum concentrations of testosterone, FSH and inhibin B after embolization treatment of males with high-grade varicocele. From 2007 to 2012, we recruited 47 male infertile patients with clinically visible left varicocele in the resting patient and at least one abnormal semen parameter. Sperm parameters and serum levels of total testosterone, FSH and inhibin B were measured prior to retrograde embolization (M0) and then 3 (M3) and 6 (M6) months afterwards. At M0, the median sperm concentration was 5.78 [0.84-37.70] × 10(6)/ejaculate. The mean ± SD sperm progressive motility, vitality and percentage of normal sperm were respectively, 21.83 ± 16.48%, 61.88 ± 15.98% and 12.88 ± 7.15%. The corresponding values at M3 were significantly higher (38.75 [3.96-95] × 10(6)/ejaculate, 29.32 ± 14.21%, 69.14 ± 14.86% and 19.03 ± 11.02%, respectively). The mean percentage of spermatozoa with a thin head was significantly lower at M6 (6.35 ± 5.29%) than at M0 (14.03 ± 13.09%). The mean serum testosterone, FSH and inhibin B levels did not change significantly over time. Em...Continue Reading

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Citations

Jan 1, 2014·Basic and Clinical Andrology·Ranjith Ramasamy
Oct 17, 2015·Human Reproduction·J AugerF Eustache
Jun 30, 2015·The Journal of Urology·Thomas F Kolon
Jun 8, 2021·Jornal Vascular Brasileiro·Sergio Quilici BelczakNathalia Almeida Cardoso da Silva
Jul 12, 2017·Gynécologie, Obstétrique, Fertilité & Sénologie·A DumontG Robin

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