Benefit of a pretreatment planning library-based adaptive radiotherapy for cervix carcinoma?

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
M GobeliRenaud de Crevoisier

Abstract

In case of intensity-modulated radiotherapy (IMRT) for locally advanced cervix carcinoma, the objectives were to quantify the difference between the planned and the delivered doses by a standard irradiation, and to estimate the dosimetric benefit of a pretreatment planning library-based adaptive radiotherapy. Ten patients with locally advanced cervix carcinoma had three planning CTs corresponding to three bladder volumes: empty, intermediate (vi) and full. On each CT, two IMRT plans were generated to deliver 45 Gy to the planning target volume (PTV), with two different margins: clinical target volume (CTV)+10mm and CTV+15 mm. Using bi-weekly CBCTs, three scenarios of treatment have been simulated and compared: standard IMRT (one vi planning) with 10 and 15 mm margins and adaptive radiotherapy with 10mm margin. The cumulated dose in the organs at risk was estimated by elastic registration. In case of standard IMRT, the cumulated dose was significantly different than the planning dose, with an under-dose of the CTV and the bladder, and an over-dose of the rectum and the peritoneal cavity. For 54% of the fractions, the adaptive radiotherapy planning was not based on vi. Considering the cumulated dose and compared to IMRT with 10-m...Continue Reading

References

Jan 5, 1999·Medical Image Analysis·J P Thirion
Jan 31, 2004·International Journal of Radiation Oncology, Biology, Physics·Christopher M LeeDavid K Gaffney
Jun 3, 2008·International Journal of Radiation Oncology, Biology, Physics·Beth M BeadlePatricia J Eifel
Aug 22, 2009·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·I Barillot
May 18, 2010·International Journal of Radiation Oncology, Biology, Physics·Karen LimUNKNOWN Gyn IMRT Consortium
Sep 14, 2010·International Journal of Radiation Oncology, Biology, Physics·James StewartMichael Milosevic
May 10, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Luiza BondarBen Heijmen
Aug 27, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·K Gnep, R Mazeron
Dec 18, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Seungjong OhYoung-Bin Cho
Feb 26, 2014·Clinical Oncology : a Journal of the Royal College of Radiologists·R JadonJ Staffurth
Apr 9, 2014·IEEE Transactions on Medical Imaging·Guillaume CazoulatPascal Haigron

❮ Previous
Next ❯

Citations

Aug 17, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Yvette SeppenwooldePetra Georg
Feb 18, 2018·Medical Physics·Bastien RigaudRenaud De Crevoisier
Sep 2, 2019·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A BadeyA Lisbona
Aug 21, 2019·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A BriensR De Crevoisier

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.