Benefits of specialisation in the management of pancreatic cancer: results of a Scottish population-based study

British Journal of Cancer
R W ParksO J Garden

Abstract

Pancreatic cancer is associated with a very poor prognosis; however, in selected patients, resection may improve survival. Several recent reports have demonstrated that concentration of treatment activity for patients with pancreatic cancer has resulted in improved outcomes. The aim of this study was to ascertain if there was any evidence of benefit for specialised care of patients with pancreatic cancer in Scotland. Records of patients diagnosed with pancreatic cancer during the period 1993-1997 were identified. Three indicators of co-morbidity were calculated for each patient. Operative procedures were classified as resection, other surgery or biliary stent. Prior to analysis, consultants were assigned as specialist pancreatic surgeons, clinicians with an interest in pancreatic disease or nonspecialists. Data were analysed with regard to 30-day mortality and survival outcome. The final study population included 2794 patients. The 30-day mortality following resection was 8%, and hospital or consultant volume did not affect postoperative mortality. The 30-day mortality rate following palliative surgical operations was 20%, and consultants with higher case loads or with a specialist pancreatic practice had significantly fewer po...Continue Reading

References

Sep 1, 1991·Current Problems in Cancer·D Kelsen, O T Atiq
Jan 1, 1996·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·P J ImperatoM B Dearie
Jul 22, 1998·Seminars in Surgical Oncology·A Nakao, H Takagi
Sep 22, 1998·Annals of Surgery·J A SosaJ L Cameron
Jul 13, 1999·Journal of the American College of Surgeons·T A GordonJ L Cameron
Apr 20, 2001·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·A S RosemurgyL C Carey
May 8, 2001·Current Problems in Cancer·M TronerP R Hulick
Jan 31, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D H BrewsterM Mackay
Feb 5, 2002·Clinical Oncology : a Journal of the Royal College of Radiologists·D HayneP Babb
Apr 12, 2002·The New England Journal of Medicine·John D BirkmeyerDavid E Wennberg
Jan 30, 2003·The British Journal of Surgery·M O BachmannI M Harvey

❮ Previous
Next ❯

Citations

Apr 7, 2005·The Lancet Oncology·David H BrewsterHans H Storm
Oct 1, 2015·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Côme LepageUNKNOWN EUROCARE-5 Working Group:
May 9, 2008·International Journal of Clinical Oncology·Donald Maxwell Parkin
Jul 25, 2006·Nature Reviews. Cancer·Donald M Parkin
Dec 25, 2010·World Journal of Surgery·John M ScollayAlastair M Thompson
May 27, 2014·World Journal of Surgery·Abu Bakar Hafeez BhattiAamir Ali Syed
Dec 19, 2015·Journal of Epidemiology and Community Health·Jeremy WalkerUNKNOWN Scottish Diabetes Research Network Epidemiology Group
Jun 13, 2013·World Journal of Surgery·Jamie YoungGillian McPhillips
Nov 23, 2013·The British Journal of Surgery·H Bismuth
Oct 22, 2013·Langenbeck's Archives of Surgery·Christina HaaneSoeren Torge Mees
Jun 28, 2013·The British Journal of Surgery·H Bismuth
May 18, 2018·Updates in Surgery·Giovanni CaprettiAlessandro Zerbi
Aug 23, 2006·Gastrointestinal Endoscopy·James A Disario
Nov 3, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R J E SkipworthS Paterson-Brown
Apr 7, 2010·The Surgical Clinics of North America·Richard K Orr

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
S R WalshF J Meyer
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
R A HawardD Forman
© 2022 Meta ULC. All rights reserved