Abstract
(1) Background: Arteriosclerosis is associated with high levels of low-density lipoprotein (LDL) cholesterol. O-methylated catechins in "Benifuuki" green tea are expected to reduce cholesterol levels, although there is limited research regarding this topic; (2) Methods: This trial evaluated 159 healthy volunteers who were randomized to receive ice cream containing a high-dose of "Benifuuki" extract including 676 mg of catechins (group H), a low-dose of "Benifuuki" extract including 322 mg of catechins (group L), or no "Benifuuki" extract (group C). Each group consumed ice cream (with or without extract) daily for 12 weeks, and their lipid-related parameters were compared; (3) Results: A significant reduction in the level of lectin-like oxidized LDL receptor-1 ligand containing ApoB (LAB) was detected in group H, compared to groups L and C. No significant differences between the three groups were detected in their levels of total cholesterol, triglycerides, and LDL cholesterol; (4) Conclusions: "Benifuuki" extract containing O-methylated catechins may help prevent arteriosclerosis.
References
Jul 29, 1992·Biochimica Et Biophysica Acta·I IkedaM Sugano
Jan 1, 1985·Journal of Chronic Diseases·L E BraitmanJ L Stanton
Dec 1, 1994·Biological & Pharmaceutical Bulletin·S MiuraI Tomita
Jan 1, 1995·Biological & Pharmaceutical Bulletin·S MiuraI Tomita
Jun 22, 1999·Circulation·H KataokaT Kita
Sep 23, 2000·Nature·A J Lusis
Nov 9, 2004·Atherosclerosis. Supplements·T R PedersenUNKNOWN Scandinavian Simvastatin Survival Study Group
Sep 30, 2005·Journal of the American College of Nutrition·Reiko Hirano-OhmoriFumitaka Ohsuzu
Sep 14, 2006·JAMA : the Journal of the American Medical Association·Shinichi KuriyamaIchiro Tsuji
Feb 14, 2007·The Journal of Nutritional Biochemistry·Sung I Koo, Sang K Noh
Jun 15, 2007·Obesity·Tomonori NagaoIchiro Tokimitsu
Dec 28, 2007·International Heart Journal·Shigenobu InamiKyoichi Mizuno
Mar 19, 2008·Atherosclerosis·Yuko SatoTatsuya Sawamura
May 20, 2008·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Dandapantula N SarmaTieraona Low Dog
May 22, 2008·JAMA : the Journal of the American Medical Association·Paul HolvoetDavid R Jacobs
Jun 19, 2008·Circulation·Yasushi IshigakiYoshitomo Oka
Nov 13, 2008·Cytotechnology·Mari Maeda-YamamotoIkuo Shibuichi
Jun 1, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kagehiro UchidaIchiro Wakabayashi
Feb 22, 2012·Journal of Agricultural and Food Chemistry·Mari Maeda-YamamotoHirofumi Tachibana
May 21, 2013·Atherosclerosis·Tomonori OkamuraUNKNOWN ERA JUMP Study Group
Feb 20, 2016·Journal of Clinical Lipidology·Tomonori OkamuraUNKNOWN SESSA Research Group
May 11, 2016·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Dimitry A ChistiakovYuri V Bobryshev