Benign epilepsy with centrotemporal spikes - Current concepts of diagnosis and treatment

Neurologia i neurochirurgia polska
P DryżałowskiJ Strzelecka

Abstract

Benign epilepsy with centrotemporal spikes (BECTS) is the most common focal epilepsy of the childhood and also one of the best known. It has a proclivity to start at a particular age and remit spontaneously before adolescence. Majority of patients may avoid long-term treatment, because of the mild course and very good outcome. Only few patients may present cognitive deficits if the proper treatment is not implied. BECTS is a part of heterogeneous group of syndromes that consists of Landau-Kleffner Syndrome (LKS), Continuous Spike-and-Wave during Sleep (CSWS) and Atypical benign partial epilepsy (ABPE). These syndromes may be also a result of various trajectories that BECTS may evolve to. Disease is suggested to have genetic origins, as some patients have relatives with different types of epilepsy. The discovery of the pathogenic mechanism of the disease and implementation of targeted therapy belong to the main challenges in the treatment of these patients.

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Citations

Mar 17, 2021·Seizure : the Journal of the British Epilepsy Association·Hasan TekgulSanem Yılmaz
Jul 6, 2021·Frontiers in Computational Neuroscience·Qiang LiCatherine J Chu
Jun 25, 2021·Frontiers in Human Neuroscience·Victoria GeorgopoulouMary H Kosmidis
Jul 25, 2021·International Journal of Molecular Sciences·Edyta DziadkowiakBogusław Paradowski
Aug 14, 2021·International Medical Case Reports Journal·Olga AnSteven Parrish Winesett

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