PMID: 9557794Apr 29, 1998Paper

Benign myoepithelioma of the skin

The American Journal of Dermatopathology
M T Fernández-FiguerasJ J Navas-Palacios

Abstract

A case of cutaneous myoepithelioma is reported. The tumor was composed of spindle-shaped, epithelioid, and plasmacytoid (hyaline) cells. It exhibited a widespread immunoreactivity for low molecular weight keratins and protein S-100, being irregularly positive for smooth muscle actin. Ultrastructural studies of tumor cells showed a variable content of intermediate filaments, with focal densities resembling smooth muscle dense bodies. A well-developed basal lamina, pinocytotic vesicles, and some desmosomes were also observed. In spite of being accepted as an individual entity, myoepitheliomas probably belong to a family of lesions that include mixed tumors. Therefore, this case can be considered as a salivary-gland-type tumor, probably originating from myoepithelial cells of sweat glands. The existence of this unique neoplasm provides further support to the debated role of myoepithelial cells in the development of mixed tumors.

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Citations

Jul 28, 2005·Der Pathologe·T Mentzel
Sep 1, 1999·Pathology International·T SasaguriY Sasaguri
Jan 22, 2002·The American Journal of Dermatopathology·Y C KimN H Myong
Feb 27, 2001·The American Journal of Surgical Pathology·H KutznerL Requena
Jan 24, 2008·The American Journal of Dermatopathology·Annalisa PatriziAlberto Righi
May 28, 2011·Pediatric Dermatology·Natacha KadlubArnaud Picard
Jan 8, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Tara D MillerWhitney D Tope
Sep 25, 2009·Journal of Cutaneous Pathology·Gillian FranklinNora J Morgenstern
Jun 12, 2009·Journal of Cutaneous Pathology·Zorica StojsicDragoljub Bacetic
Apr 22, 2008·Journal of Cutaneous Pathology·Robert M LawTerry L Barrett
Jul 21, 2007·Journal of Cutaneous Pathology·Jin TanahashiShigeo Yokoyama
Jul 28, 2011·Journal of Cutaneous Pathology·Marc Roy LewinTerry L Barrett
Jul 20, 2011·The Journal of Dermatology·Young-Jun ChoiWon-Serk Kim
Sep 3, 2013·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Markus Winther FrostLars Bjørn Stolle
Dec 18, 2013·Journal of Cutaneous Pathology·Agne NaujokasLaura B Pincus
Jul 20, 1999·Dermatologic Clinics·A R Hudson, B R Smoller
Dec 25, 2012·Foot & Ankle Specialist·Brian T DixUma Krishnamurti
Oct 10, 2014·Advances in Anatomic Pathology·Khin Thway, Cyril Fisher
Oct 8, 2019·International Journal of Surgical Pathology·Cameron WalesBrian Hinds
Oct 27, 2017·Journal of Cutaneous Pathology·Anthony P MartinezAndrew L Folpe
Jul 2, 2020·Case Reports in Pathology·Nelson MontalvoIván Ramírez
Aug 10, 2020·The American Journal of Dermatopathology·Karina FurlanIra Miller

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