Benign ulceration as a manifestation of soft tissue radiation necrosis: imaging findings.

AJNR. American Journal of Neuroradiology
J M DebnamL E Ginsberg

Abstract

The purpose of this study was to review CT imaging findings of soft tissue mucosal ulceration in patients following radiation treatment for head and neck malignancies and to correlate these with patient outcomes. The CT examinations in 20 patients with soft tissue ulceration after radiation therapy for treatment of head and neck cancer were reviewed. External beam radiation therapy was completed between 3 and 61 months (mean, 11.5 months) before the initial diagnosis of soft tissue ulceration. In all 20 patients, the initial diagnosis was made or confirmed on CT examination. Of the 20 ulcerations, 12 did not demonstrate enhancement, and the results of biopsy in 9 of these 12 were negative. Of the 12 nonenhancing ulcerations, biopsy was not performed in 3, but they have been followed clinically and radiologically for 15.7 months without evidence of recurrence. Of the 20 ulcerations, 8 demonstrated adjacent enhancement, and the results of a biopsy in 4 were positive for recurrent cancer and negative in 2; these 2 have been followed for 16.3 months without evidence of recurrence. Biopsy was not performed in 2 ulcerations, but they have been followed for 15.0 months without evidence of recurrence. For soft tissue ulceration occurri...Continue Reading

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Citations

Nov 30, 2012·Journal of Computer Assisted Tomography·Jackson D HamiltonLawrence E Ginsberg
Jun 11, 2011·Pathology Research International·J Matthew Debnam
Sep 15, 2012·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Naoko SaitoOsamu Sakai
Nov 28, 2009·AJNR. American Journal of Neuroradiology·J S YooL E Ginsberg
Nov 17, 2012·Otolaryngologic Clinics of North America·J Matthew Debnam, Nandita Guha-Thakurta
May 17, 2011·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Aditya BharathaEric S Bartlett
Aug 8, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Arthur VaroquauxMinerva Becker
Sep 23, 2011·Oral Oncology·J Matthew DebnamLawrence E Ginsberg
Nov 7, 2013·Radiation Oncology·Gabriela StuderChristoph Glanzmann
Oct 30, 2018·Clinical Nuclear Medicine·Darko PucarHadyn T Williams
Jun 12, 2021·Insights Into Imaging·Domenico AlbanoUNKNOWN Young SIRM Working Group
Dec 7, 2020·Current Problems in Diagnostic Radiology·Dinesh RaoPeter Fiester

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