Bent out of shape: RNA unwinding by the DEAD-box helicase Vasa

Cell
Patrick Linder, Paul Lasko

Abstract

RNA helicases of the DEAD-box family are involved in essentially all RNA-dependent cellular processes. In this issue of Cell, Sengoku et al. (2006) solve the structure of the DEAD-box protein Vasa in the presence of RNA and a nonhydrolyzable ATP analog and provide important insights into how this family of helicases unwinds RNA.

References

Jan 12, 1989·Nature·P LinderP P Slonimski
Jul 29, 2004·Development·Oona Johnstone, Paul Lasko
Apr 25, 2006·Cell·Toru SengokuShigeyuki Yokoyama

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