PMID: 16630807DOI: 10.1016/j.cell.2006.03.030Apr 25, 2006Paper
Bent out of shape: RNA unwinding by the DEAD-box helicase Vasa
Cell
Patrick Linder, Paul Lasko
Abstract
RNA helicases of the DEAD-box family are involved in essentially all RNA-dependent cellular processes. In this issue of Cell, Sengoku et al. (2006) solve the structure of the DEAD-box protein Vasa in the presence of RNA and a nonhydrolyzable ATP analog and provide important insights into how this family of helicases unwinds RNA.
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