PMID: 2098702Oct 1, 1990Paper

Benzoyl-arginine naphthylamide (BANA) hydrolysis by Treponema denticola and/or Bacteroides gingivalis in periodontal plaques

Oral Microbiology and Immunology
W A BretzW J Loesche

Abstract

Treponema denticola and Bacteroides gingivalis are among the few recognized species found in periodontal pockets that can hydrolyze the synthetic peptide N-benzoyl-DL-arginine-2-naphthylamide (BANA). We determined the presence of these periodontal pathogens in BANA-positive and -negative plaque samples through the use of indirect immunofluorescent antibody techniques. Eighteen of 27 diseased sites gave BANA-positive reactions, and 9 gave BANA-negative reactions. T. denticola was present in 16 of 18 BANA-positive reactions, whereas B. gingivalis was detected in 9 of the 18 BANA-positive reactions. T. denticola was present in 1 and B. gingivalis in 2 of the 9 BANA-negative reactions. Neither organism was detected in the 19 healthy sites that were negative for BANA. All measured differences between BANA-positive and BANA-negative plaques obtained in the same individuals were statistically significant. The accuracy of the BANA test, compared with clinical parameters such as bleeding upon probing and increased probing depth, was about 80%. The accuracy of the test in detecting the presence of T. denticola was 93%, for B. gingivalis, 76% and for T. denticola and/or B. gingivalis, 96%. This study indicated that BANA-positive plaques w...Continue Reading

References

Nov 1, 1988·Advances in Dental Research·W J Loesche
May 1, 1988·Journal of Clinical Periodontology·J L DzinkA D Haffajee
Apr 1, 1988·Infection and Immunity·L G SimonsonH E Morton
Jan 1, 1987·Infection and Immunity·H LarjavaM Haapasalo
Aug 1, 1985·Journal of Periodontology·W J LoescheE C Morrison
May 1, 1985·Infection and Immunity·W E MooreR R Ranney
Apr 1, 1981·Infection and Immunity·J J ZambonJ Slots
May 1, 1984·Journal of Periodontal Research·A C TannerJ M Goodson
Jun 1, 1980·Journal of Clinical Periodontology·M A Listgarten
Feb 1, 1982·Journal of Clinical Microbiology·B E LaughonW J Loesche
Nov 1, 1987·Journal of Dental Research·W A Bretz, W J Loesche

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Citations

Dec 1, 1993·Journal of Periodontology·T KojimaI Ishikawa
Nov 1, 1993·Journal of Periodontal Research·S OffenbacherR R Arnold
Jun 1, 1995·Periodontology 2000·F A Scannapieco
Apr 1, 1992·Oral Microbiology and Immunology·L G SimonsonH E Morton
May 30, 1998·Journal of Clinical Periodontology·R E PerssonH A Kiyak
Feb 28, 2008·Journal of Periodontal Research·N KobayashiK Okuda
Apr 1, 1992·Journal of Periodontology·M A Listgarten
Mar 23, 2002·Journal of Clinical Periodontology·B KuruS R Porter
Aug 1, 2003·Journal of Periodontology·UNKNOWN Research, Science and Therapy Committee
Nov 1, 1996·Annals of Periodontology·G C Armitage
Feb 16, 2002·Journal of Periodontology·Shigenobu KimuraShigeyuki Hamada
Sep 30, 2003·Journal of Periodontology·Gary C Armitage, UNKNOWN Research, Science and Therapy Committee of the American Academy of Periodontology

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