PMID: 2500401Jun 1, 1989Paper

Bepridil versus verapamil in stable angina pectoris--a controlled clinical trial

International Journal of Cardiology
H K NielsenR J Pluymers

Abstract

The calcium antagonist bepridil (bepridil monohydrochloride monohydrate, Org 5730, Cordium) was investigated in comparison with verapamil in a double-blind cross-over design in patients with angina pectoris. Exercise parameters, frequency of anginal attacks, consumption of nitroglycerin and subjective preference were analysed for 36 patients. The exercise capacity, estimated by exercise time and total work load during standard bicycle testing, was significantly more improved with bepridil treatment than with verapamil treatment. No significant differences were observed in frequencies of anginal attack, consumption of nitroglycerin and subjective preference. Side effects were mild and equally divided over both treatment groups.

References

Mar 15, 1985·The American Journal of Cardiology·L Z Benet
Jan 1, 1980·Journal of Cardiovascular Pharmacology·K A Kane, E Winslow
May 1, 1983·Journal of Cardiovascular Pharmacology·P Duchêne-MarullazJ F Trolèse
Feb 18, 1983·European Journal of Pharmacology·D C Pang, N Sperelakis
Jan 15, 1983·Biochemical Pharmacology·G Cramb, J W Dow
Jun 1, 1981·British Journal of Pharmacology·R J Marshall, A W Muir

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Citations

Aug 1, 1993·Computer Methods and Programs in Biomedicine·H P Wijnand
Jan 1, 1991·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C K van KalkenH M Pinedo

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