Berry fruit supplementation and the aging brain

Journal of Agricultural and Food Chemistry
Barbara Shukitt-HaleJames A Joseph

Abstract

The onset of age-related neurodegenerative diseases such as Alzheimer's or Parkinson's disease, superimposed on a declining nervous system, could exacerbate the motor and cognitive behavioral deficits that normally occur in senescence. In cases of severe deficits in memory or motor function, hospitalization and/or custodial care would be a likely outcome. This means that unless some way is found to reduce these age-related decrements in neuronal function, health-care costs will continue to rise exponentially. Thus, it is extremely important to explore methods to retard or reverse age-related neuronal deficits, as well as their subsequent behavioral manifestations, to increase healthy aging. In this regard, consumption of diets rich in antioxidants and anti-inflammatory polyphenolics, such as those found in fruits and vegetables, may lower the risk of developing age-related neurodegenerative diseases. Research suggests that the polyphenolic compounds found in berry fruits, such as blueberries and strawberries, may exert their beneficial effects either through their ability to lower oxidative stress and inflammation or directly by altering the signaling involved in neuronal communication, calcium buffering ability, neuroprotectiv...Continue Reading

Citations

Feb 9, 2012·European Journal of Nutrition·Lucélia TavaresCláudia N Santos
Aug 4, 2009·Journal of Neural Transmission·Andrea DreiseitelPhilipp G Sand
Dec 24, 2009·The British Journal of Nutrition·Robert KrikorianJames A Joseph
Mar 2, 2010·The British Journal of Nutrition·Hyo Geun KimMyung Sook Oh
Oct 20, 2010·The British Journal of Nutrition·Jeremy P E Spencer
Aug 22, 2012·The British Journal of Nutrition·Laura HanskeAnnett Braune
Mar 15, 2012·The Proceedings of the Nutrition Society·Catarina RendeiroJeremy P E Spencer
Jan 24, 2012·Journal of Agricultural and Food Chemistry·Marshall G Miller, Barbara Shukitt-Hale
Aug 27, 2013·Journal of Agricultural and Food Chemistry·Andreia P OliveiraPatrícia Valentão
May 8, 2009·Chemical Society Reviews·Jeremy P E Spencer
Jul 16, 2010·Journal of Medicinal Food·Marcia da Silva PintoKalidas Shetty
Dec 6, 2008·Current Opinion in Clinical Nutrition and Metabolic Care·Lauren M WillisJames A Joseph
Apr 25, 2012·Oxidative Medicine and Cellular Longevity·Sally J GustafsonThomas B Kuhn
Aug 22, 2012·Gerontology·Barbara Shukitt-Hale
Nov 16, 2012·BMC Complementary and Alternative Medicine·Rahmat Ali Khan
Aug 19, 2010·Oxidative Medicine and Cellular Longevity·Kanti Bhooshan Pandey, Syed Ibrahim Rizvi
Apr 20, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Zongyang LiTai-Ping Fan
Sep 26, 2012·Expert Review of Neurotherapeutics·Shibu M PouloseBarbara Shukitt-Hale
Jan 1, 2011·Expert Opinion on Drug Discovery·Syed Ibrahim Rizvi, Rashmi Jha
Feb 24, 2016·Frontiers in Behavioral Neuroscience·Julien BensalemPauline Lafenetre
Jun 5, 2012·Maturitas·E P Cherniack
Jan 18, 2011·Behavioural Brain Research·Magdalini A PapandreouMarigoula Margarity
Jul 8, 2016·Food Science & Nutrition·Felipe Jiménez-AspeeGuillermo Schmeda-Hirschmann
Aug 25, 2009·Neuroscience Letters·Ki Young ShinYoo-Hun Suh
Aug 19, 2010·Molecular Nutrition & Food Research·Jianbo XiaoFan Yang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Aging

Here is the latest research on intrinsic and extrinsic factors, as well as pathways and mechanisms that underlie aging in the central nervous system.

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Calcium & Bioenergetics

Bioenergetic processes, including cellular respiration and photosynthesis, concern the transformation of energy by cells. Here is the latest research on the role of calcium in bioenergetics.

Related Papers

Annals of the New York Academy of Sciences
James A JosephFrancis C Lau
Nutritional Neuroscience
Barbara Shukitt-HaleJames A Joseph
Ageing Research Reviews
Gary LynchChristine M Gall
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Chihiro TohdaKatsuko Komatsu
© 2021 Meta ULC. All rights reserved