Best MRI sequences for identifying axillary lymph node markers in patients with metastatic breast cancer: an inter-reader observational study.

European Radiology Experimental
Naziya SamreenKatrina N Glazebrook

Abstract

We assessed confidence in visualization of markers within metastatic axillary lymph nodes (LNs) on magnetic resonance imaging (MRI), which were placed post-ultrasound (US)-guided biopsy. A retrospective review was performed on 55 MRI cases between May 2015 and October 2017. Twenty-two MRIs were performed before neoadjuvant therapy, and 33 MRIs were after its initiation. There were 34/55 HydroMARK®, 10/55 Tumark®, and 11/55 other marker types. Time interval between marker placement and MRI examination was 103 ± 81 days (mean ± standard deviation). Three readers with 1-30 years of experience independently assessed four axial sequences: unenhanced fat-suppressed three-dimensional T1-weighted spoiled gradient-recalled (SPGR), first contrast-enhanced fat-suppressed SPGR, T2-weighted water-only fast spin-echo (T2-WO), and T2-weighted fat-only fast-spin-echo (T2-FO). Markers were 5.2× more likely to be visualized on T2-WO than on unenhanced images (p = < 0.001), and 3.3× more likely to be visualized on contrast-enhanced than on unenhanced sequences (p = 0.009). HydroMARK markers demonstrated a 3× more likelihood of being visualized than Tumark (p = 0.003). Markers were 8.4× more likely to be visualized within morphologically abnormal ...Continue Reading

References

Mar 25, 2004·AJR. American Journal of Roentgenology·Alain LucianiAlain Rahmouni
Feb 10, 2010·Annals of Surgical Oncology·Sara JavidMehra Golshan
Oct 11, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jacob S EcanowJan M Jeske
Jan 27, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Abigail S CaudleHenry M Kuerer
Jun 23, 2016·Journal of Chiropractic Medicine·Terry K Koo, Mae Y Li
Nov 5, 2016·AJR. American Journal of Roentgenology·Gaiane M RauchWei Tse Yang
Mar 21, 2018·Current Problems in Surgery·Ismail Jatoi, John R Benson
Sep 29, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sirishma KalliManisha Bahl

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies
dissection

Software Mentioned

JMP
Tumark

Related Concepts

Related Feeds

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.