Best single-slice location to measure visceral adipose tissue on paediatric CT scans and the relationship between anthropometric measurements, gender and VAT volume in children

The British Journal of Radiology
Michelle O'ConnorShane Foley

Abstract

Visceral adipose tissue (VAT) is a significant risk factor for obesity-related metabolic diseases. This study investigates (1) the best single CT slice location for predicting total abdominal VAT volume in paediatrics and (2) the relationship between waist circumference (WC), sagittal diameter (SD), gender and VAT volume. A random sample of 130 paediatric abdomen CT scans, stratified according to age and gender, was collected. Three readers measured VAT area at each intervertebral level between T12 and S1 using ImageJ analysis (National Institute of Health, Bethesda, MD) software by thresholding -190 to -30 HU and manually segmenting VAT. Single-slice VAT measurements were correlated with total VAT volume to identify the most representative slice. WC and SD were measured at L3-L4 and L4-L5 slices, respectively. Regression analysis was used to evaluate WC, SD and gender as VAT volume predictors. Interviewer and intraviewer reliability were excellent (intraclass correlation coefficient = 0.99). Although VAT measured at multiple slices correlated strongly with abdominal VAT, only one slice in females at L2-L3 and two slices in males at L1-L2 and L5-S1 were strongly correlated across all age groups. Linear regression analysis showe...Continue Reading

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Citations

May 4, 2018·Diseases of the Colon and Rectum·Weisong ShenWeiming Zhu
Jun 28, 2018·Journal of Crohn's & Colitis·Weisong ShenWeiming Zhu
Mar 31, 2019·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Henry S KahnSharon Saydah
Apr 9, 2019·Critical Care Medicine·Chengsi OngZudin A Puthucheary
Aug 18, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Radka Taxová BraunerováJoão Breda
Oct 19, 2021·Frontiers in Nutrition·Kacper MarunowskiMaciej Piskunowicz

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