PMID: 9529612Apr 8, 1998Paper

Beta-catenin: a key mediator of Wnt signaling

Current Opinion in Genetics & Development
K Willert, R Nusse

Abstract

Beta-catenin is a pivotal player in the signaling pathway initiated by Wnt proteins, mediators of several developmental processes. beta-catenin activity is controlled by a large number of binding partners that affect the stability and the localization of beta-catenin and is thereby able to participate in such varying processes as gene expression and cell adhesion. Activating mutations in beta-catenin and in components regulating its stability can contribute to the formation of certain tumors.

References

Jun 26, 1992·Cell·R Nusse, H E Varmus
Mar 28, 1995·Proceedings of the National Academy of Sciences of the United States of America·S MunemitsuP Polakis
May 1, 1995·Genes & Development·S YanagawaR Nusse
Dec 1, 1994·The Journal of Cell Biology·J HülskenJ Behrens
Jun 1, 1994·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·E Siegfried, N Perrimon
Jan 6, 1994·Nature·E SiegfriedN Perrimon
Dec 10, 1993·Science·B RubinfeldP Polakis
Sep 1, 1996·The Journal of Cell Biology·Y S TaoP D McCrea
Jun 15, 1996·Journal of Cellular Biochemistry·H AberleR Kemler
May 15, 1997·Nature·D I StruttM Mlodzik
Jun 7, 1997·Biochimica Et Biophysica Acta·P Polakis
Jul 1, 1997·The EMBO Journal·H AberleR Kemler

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Citations

Nov 1, 2000·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·N Barker, H Clevers
Oct 7, 2003·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Lifang LiuHongyun Liu
Oct 5, 2010·Histochemistry and Cell Biology·Albert BraeuningMichael Schwarz
Sep 2, 2004·Journal of Cancer Research and Clinical Oncology·Gerhard EisenbrandStephan Muehlbeyer
Feb 16, 2005·Apoptosis : an International Journal on Programmed Cell Death·W V ZhangN S Stott
May 5, 2006·Apoptosis : an International Journal on Programmed Cell Death·M JülligN S Stott
Aug 9, 2011·Journal of Molecular Histology·Sandra SchreiberChristoph Köhle
Sep 1, 2006·Reviews in Endocrine & Metabolic Disorders·Mark L Johnson, Nalini Rajamannan
Jun 12, 2012·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Chao ZhangXu Zhang
Jul 13, 2007·Stem Cell Reviews·Tzung-Hai Yen, Nicholas A Wright
Aug 14, 2012·Molecular Neurobiology·Maria Laura GiuffridaAgata Copani
May 18, 2005·Molecular and Cellular Endocrinology·Janice M KerrWilliam M Wood
Dec 18, 2003·Gene Expression Patterns : GEP·Sangeeta Dhawan, K P Gopinathan
Mar 29, 2008·Cell Stem Cell·Aniruddha J Deshpande, Christian Buske
Jul 31, 2002·Biochemical and Biophysical Research Communications·Song Ja KimJang Soo Chun
Jan 5, 2002·European Journal of Pharmacology·V Y WongD P Brooks
Aug 14, 2003·Experimental Cell Research·Arlene R Wechezak, Daniel E Coan
Oct 22, 2003·Experimental Cell Research·Eun-Kyung Suh, Barry M Gumbiner
May 28, 2003·Trends in Pharmacological Sciences·Andrea CaricasoleFerdinando Nicoletti
Dec 12, 2001·Neuroscience·W M FreemanK E Vrana
Jun 1, 2002·Gene·Meredith C DurmowiczDavid Schlessinger
Jun 9, 2001·Clinics in Dermatology·G E Rogers, P I Hynd
May 15, 2002·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Mitsuhiko Yamada, Teruhiko Higuchi
Jun 4, 1999·Mechanisms of Development·R ReifegersteM Wegner
Nov 18, 1998·Current Opinion in Cell Biology·A Ben-Ze'ev, B Geiger
Nov 18, 1998·Current Opinion in Cell Biology·T D Tlsty
Oct 6, 1999·Current Opinion in Cell Biology·M S Steinberg, P M McNutt
Apr 21, 1999·Current Opinion in Cell Biology·Q Eastman, R Grosschedl
Nov 27, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E Van CutsemJ Wils
Mar 10, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·F Marks, G Fürstenberger
Aug 21, 2002·Trends in Cell Biology·Chad A Cowan, Mark Henkemeyer
Jan 1, 2003·Seminars in Cancer Biology·Sharon Amit, Yinon Ben-Neriah
Jul 17, 2013·Immunology and Cell Biology·Chih-Chia LiangChun-Ming Chen
May 13, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Patricia E EllisAllan B MacLean
Jan 25, 2005·Nature Immunology·Andrew W DuncanTannishtha Reya

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