PMID: 19912850Apr 1, 1992Paper

beta-Endorphin-immunoreactive neurons in the hypothalamus and medulla of the rat brain: Effect of prenatal ethanol

Molecular and Cellular Neurosciences
R A Baker, W J Shoemaker

Abstract

The number and distribution of beta-endorphin neurons in the hypothalamus and medulla of rats is compared among three experimental treatment groups: prenatally ethanol-exposed rats, pair-fed control rats, and normally fed control rats. Quantitative analysis of beta-endorphin-immunoreactive neurons in 12 sections through the rostral-caudal extent of the mediobasal hypothalamus revealed no significant difference in the total number or distribution of beta-endorphin neurons among any of the three treatment groups. The mean number of beta-endorphin neurons was consistently less in each of the 12 sections of pair-fed rats compared to normally fed rats, but there was no consistent difference between the mean number of neurons/section in prenatally ethanol-exposed rats compared to the normally fed controls. The distribution and time of appearance of a second population of beta-en-dorphin neurons was analyzed in the caudal medulla. beta-endorphin-immunoreactive neurons were easily visualized in the caudal medulla of rats from each treatment group on Postnatal Days 9-11. However, this population could not be identified with antisera against beta-endorphin on Postnatal Days 19-21 in any treatment group, even though neurons in the hypotha...Continue Reading

References

Mar 1, 1990·The Journal of Comparative Neurology·M W Miller, G Potempa
Jun 1, 1988·Alcoholism, Clinical and Experimental Research·M W Miller
Mar 1, 1986·Alcoholism, Clinical and Experimental Research·J R WestM D Cassell
Mar 1, 1987·Behavioral and Neural Biology·J H HanniganE P Riley
Feb 1, 1946·The Anatomical Record·M ABERCROMBIE

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Citations

Nov 1, 1993·Peptides·G A OlsonA J Kastin
Jun 1, 1995·Alcoholism, Clinical and Experimental Research·R A Baker, W J Shoemaker
Apr 1, 1996·Alcoholism, Clinical and Experimental Research·C Rivier
Jul 11, 1998·Alcoholism, Clinical and Experimental Research·R F McGivernR J Handa
Nov 11, 2021·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Marissa J MetzShane T Hentges

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