Beta-endorphin levels in the follicular fluid of human oocytes fertilized in vitro

Gynecologic and Obstetric Investigation
R TepperD M Serr

Abstract

This study was carried out in order to investigate the relationship between beta-endorphin (beta-ep) levels in plasma and follicular fluid and fertilization rates of oocytes from women undergoing treatment in our in vitro fertilization and embryo transfer program. Nine women suffering from severe tubal damage, with regular menstrual cycles, were studied. Follicular growth was induced with clomiphene citrate, combined with human menopausal gonadotropins. Analysis of follicular fluids and plasma showed no significant difference in beta-ep levels. The larger follicles (greater than 2 ml volume) had significantly higher beta-ep levels than smaller follicles (less than 2 ml volume; p less than 0.001); however, there was no significant difference in the fertilization rates of their oocytes.

Citations

Jan 1, 1993·Molecular Reproduction and Development·R SakakibaraM Ishiguro
Nov 29, 2020·Archives of Gynecology and Obstetrics·Chan ZhangFang Wang

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