Nov 1, 1976

beta-Glucuronidase and oestrogens in hydatidiform mole

Clinica Chimica Acta; International Journal of Clinical Chemistry
K C LeungC C Yu

Abstract

The activity of beta-glucuronidase (beta-D-glucuronide glycuronohydrolase, EC 3.2.1.31) in placental and hydatidiform mole tissue and in sera from non-pregnant, normal and molar pregnant women was determined. The oestrogen concentrations in the two solid tissues were also assayed. Significant differences were found in the activities of the enzyme between placental and molar tissues and among the various sera. The lower activity in molar serum corresponds to a lower concentration of oestrogens in molar tissues and may be regarded as a response to the alleviation of conjugation requirements.

  • References4
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References

  • References4
  • Citations1

Citations

Mentioned in this Paper

Conjugation
Uterine Cancer
Placenta
Beta-glucuronidase
Hydatidiform Mole
Phosphoglycerate Dehydrogenase Activity
Exo-beta-D-Glucuronidase
GUSB
Molar Tooth
PHGDH wt Allele

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