Beta human chorionic gonadotrophin in serum and urine. A marker for metastatic urothelial cancer.

British Journal of Urology
R IlesT Chard

Abstract

Beta human chorionic gonadotrophin (beta HCG) was measured in 127 urine and 85 serum samples from 175 untreated patients with urothelial cancer. Serum levels of beta HCG were substantially elevated in 16 of 21 patients (76%) with widespread metastases but in only 2 of 64 patients (3%) with disease confined to the pelvis. Urine beta HCG levels were moderately raised in 11 of 25 patients (44%) with locally advanced disease, but greatly elevated in 5 of 7 patients (71%) with metastases. Measurement of serum and/or urine beta HCG appears to be an efficient diagnostic marker for the presence of distant metastases in bladder carcinoma.

References

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Citations

Jan 1, 1995·International Urology and Nephrology·S BaltaciK Sarica
Jan 1, 1994·International Urology and Nephrology·Z F DobrowolskiM Dolezal
Dec 20, 1996·Molecular and Cellular Endocrinology·H Alfthan, U H Stenman
Jun 6, 2009·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Mahul B Amin
Apr 29, 2008·Cancer Treatment Reviews·D FurnissUNKNOWN National Cancer Research Institute Renal Clinical Studies Group
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Sep 16, 2020·The American Journal of Surgical Pathology·Christopher G PrzybycinRoni M Cox

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