Betaine-induced stimulation of respiration at high osmolarities in a halotolerant bacterium.

The Biochemical Journal
C Shkedy-Vinkler, Y Avi-Dor

Abstract

It was shown that non-penetrating solutes at high concentrations inhibit the respiration of the halotolerant bacterium Ba1. Betaine relieved the inhibition caused by osmotic stress and exhibited in this respect a considerable structural specificity. The rate of oxidation of various substrates was stimulated to different extents. It stimulated the rates of both respiration and growth to a similar extent, leaving the energy yield essentially unchanged. In cells pre-loaded with labelled glutamate, betaine also stimulated the rate of oxidation of this intracellular substrate. Betaine was accumulated by respiring cells, and the maximum amount taken up was correlated with the osmolarity of the medium. As judged by chromatography, accumulated intracellular betaine underwent no chemical modification, and this accumulated betaine could not be exchanged with the betaine in the medium or released by passive efflux when respiration was inhibited. Intracellular betaine caused no stimulation of respiration, whereas betaine added to the medium increased the respiratory rate to the same extent in cells pre-loaded with betaine as that in the nonloaded cells. The above observations suggest that iso-economic adjustment is not involved in the anti...Continue Reading

Citations

Jan 1, 1987·Critical Reviews in Microbiology·R H Vreeland
Jan 1, 1982·Archives of Biochemistry and Biophysics·R Shnaiderman, Y Avi-Dor
Mar 1, 1984·Archives of Biochemistry and Biophysics·S Ken-DrorY Avi-Dor
Jul 1, 1983·Archives of Biochemistry and Biophysics·T Arakawa, S N Timasheff
Jan 1, 1988·Society for Applied Bacteriology Symposium Series·I R BoothC F Higgin
Jan 1, 1980·Planta·D M DicksonJ Davenport
Sep 13, 2011·Bioprocess and Biosystems Engineering·Sang Jun LeeSeung Wook Kim
Nov 5, 2013·Bioprocess and Biosystems Engineering·Laxmi Prasad ThapaSeung Wook Kim
Dec 1, 1976·Bacteriological Reviews·A D Brown
Jul 1, 1983·Applied and Environmental Microbiology·D Le Rudulier, L Bouillard
Jun 10, 1998·Microbiology and Molecular Biology Reviews : MMBR·A VentosaA Oren
Mar 1, 1983·Journal of Bacteriology·D J KushnerR A MacLeod
Jan 1, 1986·Archives of Biochemistry and Biophysics·S Ken-DrorY Avi-Dor

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