Abstract
To study the between-scanner variation and the between-visit reproducibility of brain apparent diffusion coefficient (ADC) measurements in the setting of a multi-center chemotherapy clinical trial for glioblastoma multiforme. ADC maps of 52 patients at six sites were calculated in-house from diffusion-weighted images obtained by seven individual scanner models of two vendors. The median and coefficient of variation (CV) of normal brain white matter ADC values from a defined region of interest were used to evaluate the differences among scanner models, vendors, magnetic fields, as well as successive visits. All patients participating in this study signed institutional review board approved informed consent. Data acquisition was performed in compliance with all applicable Health Insurance Portability and Accountability Act regulations. The study spanned from August 1, 2006, to January 29, 2008. For baseline median ADC, no difference was observed between the different scanner models, different vendors, and different magnetic field strength. For baseline ADC CV, a significant difference was found between different scanner models (p = 0.0002). No between-scanner difference was observed in ADC changes between two visits. For between-...Continue Reading
References
Dec 1, 1996·Radiology·C PierpaoliG Di Chiro
Jan 1, 1997·Magnetic Resonance Imaging·D XingL D Hall
Aug 1, 2000·AJR. American Journal of Roentgenology·S T EngelterJ R MacFall
Nov 4, 2000·Radiology·P W SchaeferR G Gonzalez
Dec 21, 2000·Journal of the National Cancer Institute·T L ChenevertB D Ross
Mar 29, 2001·Journal of Magnetic Resonance Imaging : JMRI·D Le BihanH Chabriat
Dec 19, 2002·NMR in Biomedicine·Peter J Basser, Derek K Jones
Feb 22, 2003·European Journal of Radiology·Roland Bammer
Mar 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yael MardorThomas Tichler
Aug 26, 2003·Nihon Hoshasen Gijutsu Gakkai zasshi·Koji KoizumiA Kobayashi
Nov 18, 2003·European Radiology·Stefan C A SteensMark A van Buchem
Mar 15, 2006·European Radiology·Thierry A G M HuismanKamil A Il'yasov
Jun 8, 2006·Neoplasia : an International Journal for Oncology Research·Bradford A MoffatBrian D Ross
Nov 10, 2006·NeuroImage·David BonekampAlena Horská
May 29, 2007·NeuroImage·Bennett A LandmanSusumu Mori
Aug 31, 2007·Journal of Magnetic Resonance Imaging : JMRI·Jonathan A D FarrellSusumu Mori
Dec 1, 2007·Journal of Magnetic Resonance Imaging : JMRI·Jeffrey J Neil
Oct 22, 2008·Radiology·Makoto SasakiUNKNOWN Acute Stroke Imaging Standardization Group-Japan (ASIST-Japan) Investigators
Feb 4, 2009·Neoplasia : an International Journal for Oncology Research·Anwar R PadhaniPeter L Choyke
Jun 30, 2009·Radiology·Whitney B PopeJonathan Goldin
Citations
Mar 27, 2020·Investigative Radiology·Akifumi HagiwaraShigeki Aoki
Jan 28, 2021·Cancers·Francesco SanvitoAndrea Falini
Jul 27, 2018·Magnetic Resonance Imaging·Xiaopeng ZhouMark J Lowe
Aug 15, 2021·Japanese Journal of Radiology·Toshiaki TaokaShinji Naganawa
Nov 21, 2021·Human Brain Mapping·Nabin KoiralaNicole Landi