PMID: 32668865Jul 17, 2020Paper

Bevacizumab plus UFT Regimen for Four Patients with Stage Ⅳ Colorectal Cancer Receiving Hemodialysis

Gan to kagaku ryoho. Cancer & chemotherapy
Tetsuro TakayamaKengo Asami

Abstract

We present case reports of 4 patients on hemodialysis with Stage Ⅳ colorectal cancer who received regular dose bevacizumab( twice per week)plus a daily dose of UFT chemotherapy. This regimen was safe and effective in the long-term for these patients without requiring changes in the hemodialysis schedule. The 4 patients were 71, 75, 67, and 66-year-old men who received bevacizumab 32, 49, 22, and 63(ongoing)times, respectively. Progression-free survivalwas 16, 28, 15, and 30 months, respectively; no severe side effects occurred during this therapy. It is possible that the bevacizumab plus UFT regimen may be acceptable in patients with Stage Ⅳ colorectal cancer receiving hemodialysis.

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