Beyond Biological Chelation: Coordination of f-Block Elements by Polyhydroxamate Ligands

Chemistry : a European Journal
A Kirstin Sockwell, Modi Wetzler

Abstract

The promise of polyhydroxamic acid ligands for the selective chelation of the f-block elements is becoming increasingly more apparent. The initial studies of polyhydroxamic acid siderophores showed the formation of highly stable complexes with PuIV , but a higher preference for FeIII hindered effective applications. The development of synthetic routes toward highly pure and customizable ligands containing multiple hydroxamic acids allowed for the growth of new classes of compounds. Although the first round of these ligands focused on the incorporation of siderophore-like frameworks, the new synthetic strategies led to small molecules of various frameworks and even resins for applications in the field of f-block element separations and biological desorption. Unfortunately, a lack of consistent stability-constant data makes direct comparisons across this body of work difficult. More studies into the stability constants and separations of the f-block elements in a variety of pH ranges is necessary to truly realize the potential for polyhydroxamic acid ligands.

References

Nov 30, 1988·Biochemical and Biophysical Research Communications·A ShanzerT Emery
Jun 16, 1967·Science·J B Neilands
Jan 1, 1983·Critical Reviews in Clinical Laboratory Sciences·G D McLarenR W Kellermeyer
Mar 30, 1984·Biochemical and Biophysical Research Communications·T EmeryR K Olsen
Apr 10, 1982·British Medical Journal·B ModellD J Weatherall
Jul 1, 1980·Journal of Bacteriology·A Hartmann, V Braun
Mar 1, 1996·Environmental Health Perspectives·S Hirano, K T Suzuki
Aug 2, 2001·Environmental Science & Technology·S G JohnM P Neu
Apr 12, 2002·Environmental Science & Technology·Stephan M KraemerGarrison Sposito
Dec 1, 1964·Proceedings of the Society for Experimental Biology and Medicine·M W ROSENTHAL, A LINDENBAUM
Nov 13, 2003·Chemical Reviews·Anne E V GordenPatricia Durbin
Apr 9, 2010·Natural Product Reports·Robert C Hider, Xiaole Kong
Jul 19, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Manuel Sturzbecher-HoehneRebecca J Abergel
Jul 18, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Guoxin TianLinfeng Rao
Nov 10, 2012·Inorganic Chemistry·Kate MaherGordon E Brown
Mar 1, 2013·Metallomics : Integrated Biometal Science·Gauthier J-P DeblondeRebecca J Abergel
Mar 13, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Timothy C Johnstone, Elizabeth M Nolan

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