Beyond Irritable Bowel Syndrome: The Efficacy of the Low Fodmap Diet for Improving Symptoms in Inflammatory Bowel Diseases and Celiac Disease

Digestive Diseases
Anna TestaFabiana Castiglione

Abstract

To evaluate the usefulness of a low FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) diet on patients with irritable bowel syndrome (IBS), non-active inflammatory bowel diseases (IBD), and celiac disease (CD) on a gluten-free diet (GFD). Dietetic interventional prospective study. IBS, IBD, and CD subjects were evaluated to check if they fulfilled the Rome III criteria. Each subject was educated to follow a low FODMAP diet after being evaluated by filling out questionnaires that assessed the quality of life (QoL) and symptoms experienced (IBS-SSS and SF-36), and was reevaluated after 1 and 3 months. One hundred twenty-seven subjects were enrolled: 56 with IBS, 30 with IBD, and 41 with CD. IBS-SSS showed that abdominal symptoms improved after 1 and 3 months of diet in all subjects, with significant difference among the 3 groups at T0 (average scores IBS: 293 ± 137, IBD: 206 ± 86, CD: 222 ± 65, p < 0.001), but no difference at T3 (IBS: 88 ± 54, IBD: 73 ± 45, CD: 77 ± 49, p = ns). By analyzing the SF-36 questionnaire, we did not observe any difference between the 3 groups, in terms of response to diet (p = ns), we observed a clinical improvement from T0 to T3 for most of the questionnaire's domains...Continue Reading

References

Jul 18, 1992·BMJ : British Medical Journal·J E BrazierL Westlake
Feb 1, 1997·The American Journal of Clinical Nutrition·S Mishkin
Dec 22, 1999·Journal of Clinical Gastroenterology·M W RussoD A Drossman
Dec 23, 2003·Cytokine·J García-HerreraM J Rodríguez-Yoldi
Nov 5, 2005·Alimentary Pharmacology & Therapeutics·E B AndrewsA W Mangel
Feb 14, 2006·Gut·M Simrén, P-O Stotzer
May 9, 2006·Gastroenterology·George F LongstrethRobin C Spiller
Sep 27, 2006·Journal of the American Dietetic Association·Susan J Shepherd, Peter R Gibson
Sep 11, 2007·Inflammatory Bowel Diseases·Catherine CroaghPeter R Gibson
Jun 19, 2009·The American Journal of Gastroenterology·UNKNOWN American College of Gastroenterology Task Force on Irritable Bowel SyndromeEamonn M M Quigley
Feb 9, 2010·Journal of Gastroenterology and Hepatology·Peter R Gibson, Susan J Shepherd
Jan 13, 2011·The American Journal of Gastroenterology·Jessica R BiesiekierskiPeter R Gibson
Feb 11, 2012·The British Journal of Nutrition·Federico BiagiGino Roberto Corazza
Feb 22, 2012·Gut·Jonas F LudvigssonCarolina Ciacci
Aug 30, 2012·The American Journal of Gastroenterology·Stephen J Halpin, Alexander C Ford
Apr 3, 2013·The American Journal of Gastroenterology·Shanti EswaranWilliam D Chey
May 25, 2013·International Journal of Clinical Practice·R H de RoestR B Gearry
Jun 15, 2013·The American Journal of Nursing·Joyce K AnastasiMichelle Chang
Oct 1, 2013·Gastroenterology·Emma P HalmosJane G Muir
Feb 15, 2015·Gastroenterology·Peter R GibsonJane G Muir
May 3, 2016·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Nicola ImperatoreRaffaella Tortora
May 14, 2016·Alimentary Pharmacology & Therapeutics·S ChristodoulidesS M Scott
Nov 17, 2016·Minerva gastroenterologica e dietologica·Nicola ImperatoreNicola Caporaso
Mar 1, 2017·Journal of Gastroenterology and Hepatology·Jane VarneyJane G Muir
Apr 12, 2017·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Nicola ImperatoreAntonio Rispo
Jun 2, 2017·World Journal of Gastroenterology : WJG·Natalia PedersenPia Munkholm
Jul 15, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·M O'KeeffeM C Lomer
Jul 26, 2017·World Journal of Gastroenterology : WJG·Ruth M HarvieMichael Schultz

❮ Previous
Next ❯

Citations

Feb 13, 2019·Minerva gastroenterologica e dietologica·Prianka Gajula, Eamonn M Quigley
Nov 2, 2019·Expert Review of Gastroenterology & Hepatology·James B AdamsMichael J Sadowsky
Aug 15, 2019·Journal of Medical Internet Research·Martín Pérez-PérezAnália Lourenço
Feb 20, 2020·European Journal of Nutrition·Iolanda CioffiFabrizio Pasanisi
Aug 23, 2019·Nutrients·Walburga Dieterich, Yurdagül Zopf
Jun 4, 2019·Frontiers in Pediatrics·Shakira Yoosuf, Govind K Makharia
Apr 29, 2020·Scientific Reports·Marina Moreira de CastroMarciane Milanski
Nov 16, 2020·The Lancet. Gastroenterology & Hepatology·Imran Aziz, Magnus Simrén
Jan 28, 2021·Journal of Clinical Medicine·Spyros PeppasStefanos Bonovas
Feb 16, 2021·World Journal of Experimental Medicine·Marina Moreira de CastroRaquel Franco Leal
Feb 5, 2021·Frontiers in Medicine·María de Lourdes MorenoCarolina Sousa
Jan 19, 2020·Journal of the Academy of Nutrition and Dietetics·Feon W Cheng, Deepa Handu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved